Infectious Disease General
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Infectious Disease Updates
Lyme Disease; Pregnant Women Must Be Screened for Syphilis; Pacific Coast Tick Fever
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Cephalexin Beat Cefdinir for Treating Uncomplicated UTI in Women
Cefdinir was inferior to cephalexin in the treatment of uncomplicated urinary tract infections in women due to a high rate of early recurrence.
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Comprehensive Data Analysis Validates the Effectiveness and Safety of COVID-19, RSV, and Influenza Vaccination
Respiratory syncytial virus, influenza, and COVID-19 vaccines are safe and effective.
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COVID-19 Vaccine Receipt Was Associated with Better Clinical Outcomes in U.S. Veterans
An observational study from the Department of Veterans Affairs found that individuals who received the 2024-2025 COVID-19 vaccine and the influenza vaccine on the same day had fewer emergency department visits, COVID-19-associated hospitalizations, and deaths related to COVID-19 compared to a group that only received the influenza vaccine.
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Imposed Diagnostic Stewardship and Pediatric Blood Cultures
A children’s hospital developed a strategy to restrict indications for ordering blood cultures when supply chain problems led to a shortage of blood culture bottles. Evaluating outcomes, they realized that the imposed diagnostic stewardship preserved resources without harm to patients; they subsequently continued to impose restrictions on ordering blood cultures even when supplies were available.
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An Oral Vaccine Against Salmonella Paratyphi A Shows Promise
In a Phase IIb controlled human infection model study, the oral live attenuated vaccine CVD 1902 demonstrated 73% efficacy against Salmonella Paratyphi A infection, with a favorable safety profile and robust immunogenicity, supporting advancement toward field trials in endemic populations.
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Emerging Infectious Diseases
Emerging infectious diseases may be defined as infectious diseases that are either new to a specific population or that are rapidly increasing in both incidence and geographic range. As the front line for healthcare, emergency physicians should be aware of the potential threats developing around the globe, as well as the constant threat that emerging infectious diseases pose to public health. This article will detail seven of the most threatening emerging infectious diseases in terms of increasing spread, severity, and lethality.
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Infectious Disease Updates
Emerging Carbapenemase Resistance in Enterobacterales; Jamestown Canyon Virus Common in Northern Minnesota and Wisconsin
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Chikungunya in New York
On Aug. 21, 2025, a 60-year-old woman living in Nassau County on Long Island became ill with symptoms that were marked by severe joint pain involving her feet, ankles, knees, wrists, hands, and shoulders.
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Enterococcal Infections: Getting More Difficult to Treat
Increasing resistance among enterococci dictates the need for careful antibiotic choices, even in the absence of high-quality clinical data.