Browse Neurology Alert Articles by Topic

Small Vessel Disease Often Accompanies Large Vessel Intracranial Atherosclerosis

The SAMMPRIS trial investigated the consequences of medical vs endovascular therapy for the treatment of symptomatic intracranial atherosclerosis, and points out the high prevalence of coexisting small vessel disease with large vessel atherosclerosis.

Loss of Consciousness at Onset of Aneurysmal SAH: Poor Prognosis

Loss of consciousness at onset of Aneurysmal subarachnoid hemorrhage is an indicator of early brain injury and predicts poor functional outcome or death at 12 months.

Left Atrial Dysfunction Without Fibrillation Increases Stroke Risk

Lleft atrial abnormalities that do not necessarily result in atrial fibrillation, may also increase the risk of stroke and should be investigated and searched for in patients with ischemic stroke consistent with cardiogenic embolism.

Vision Problems After Ischemic Stroke: Effects on Quality of Life

Visual impairments are common in stroke survivors and should prompt a careful ophthalmologic evaluation, since many of the problems are ocular and not neurological.

Acetylcholine Receptor Antibody Testing in Ocular Myasthenia Gravis

More than two-thirds of patients with ocular myasthenia will have a positive antibody test, and a high level may predict progression to generalized disease.

Simvastatin and Vitamin D for Migraine Prevention

In a randomized, double-blind, placebo-controlled trial of 57 adults with episodic migraine, simvastatin plus vitamin D was effective in the prevention of headache in adults with episodic migraine.

Disability, Anxiety, and Depression with Medication-overuse Headache

A brief intervention that focuses on patient education can be effective in reducing headache frequency and medication dependency in patients with medication overuse headache.

Clinical Features and Treatment Response in Patients with NMO Spectrum Disorders

In a retrospective analysis of 871 relapses in 185 patients with neuromyelitis optica or an neuromyelitis optica spectrum disorder, the authors reported that more than 80% of patients will have a partial or complete remission from their initial course of therapy.

Carotid Occlusion Rarely Develops from Asymptomatic Carotid Artery Stenosis

The risk of progression to carotid occlusion is well below the risk of carotid stenting or carotid endarterectomy, and intensive medical therapy appears to be preferred for the vast majority of patients with asymptomatic carotid artery stenosis.

Postmortem Evidence of Limbic, Neocortical, and Basal Ganglia Deficits in Parkinson’s Disease Dementia

Postmortem brain tissue from 15 individuals with Parkinson’s disease dementia was analyzed by high-performance liquid chromatography and immunoassays, revealing widespread deficits in dopamine, serotonin, and noradrenaline innervation.