Neurology
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Submentalis REM Sleep Muscle Activity: A Potential Biomarker for Synucleinopathy
Objective findings during polysomnography (REM sleep without atonia), as diagnosed with submentalis EMG recordings, may be a biomarker for synucleinopathies, such as Parkinson’s disease and multiple system atrophy.
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Fluctuating Cognition: An Often-Neglected Feature of Lewy Body Dementias
Clinical identification of fluctuating cognition is challenging. A better understanding of potential etiological mechanisms can allow for optimization of clinical assessment tools and targeted therapeutic approaches.
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Neuropathology and Dementia in Football Players With CTE
The authors of a cross-sectional study involving analysis of data from the ongoing Understanding Neurologic Injury and Traumatic Encephalopathy (UNITE) study found that dementia is likely a result of neuropathologic changes associated with repetitive head injury as well as non-head trauma-associated vascular pathologic changes in patients with chronic traumatic encephalopathy.
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Significance of Brain Microbleeds After Traumatic Brain Injury
Traumatic microbleeds are common in patients with any severity of traumatic brain injury and may be a useful biomarker to predict clinical outcomes.
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Cefiderocol Injection (Fetroja)
Cefiderocol should be prescribed to treat complicated urinary tract infections, including pyelonephritis, in adults ≥ 18 years of age with limited or no alternative treatment options.
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Vegetarians and Stroke
A recent study revealed vegetarians have a 22% lower incidence of ischemic heart disease, but a 20% increased incidence of total stroke, mostly related to hemorrhagic stroke, when compared to meat eaters.
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Clostridioides difficile Infection: Fecal Microbiota Transplantation vs. Antibiotics
Relative to vancomycin or metronidazole treatment of recurrent Clostridioides difficile infection, treatment with fecal microbiota transplantation is associated with a lower risk of bloodstream infection, shorter hospital length of stay, and improved survival.
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Dual Antiplatelet Therapy Increases Serious Hemorrhages Following TIA or Minor Stroke
Caution should be taken and close observation of patients maintained when treating with dual antiplatelet therapies.
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Soft Drinks and Death
Investigators found drinking more soft drinks, both artificially sweetened and sugar-sweetened, is associated with a higher risk of death, cardiovascular illness, and digestive illnesses.
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Airplane-Triggered Headaches
Severe, unilateral headaches that occur during airplane travel, particularly during landing, are most likely a variant of migraine headaches triggered by changes in cabin pressure.