Browse Neurology Articles by Topic

What Is the Optimal Blood Pressure for Secondary Prevention of Stroke?

Investigators terminated a study early before they could draw any firm conclusions. Thus, there remains a lack of solid evidence to support a firm recommendation regarding optimal blood pressure management for secondary stroke prevention.

Dapagliflozin Treatment Improves Life Quality for Systolic Heart Failure Patients

Treatment with dapagliflozin for 12 weeks resulted in improved health status, either a reduction in NT-proBNP or improvement in quality of life measures, in systolic heart failure patients with or without type 2 diabetes mellitus.

Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?

An individual-participant meta-analysis of prospective studies revealed menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.

Can You Interpret This Rhythm?

The long lead II rhythm strip in the figure was obtained from a middle-aged woman with syncope and hypotension. What can you say about the rhythm?

Minocycline Topical Foam (Amzeeq)

Minocycline topical foam is indicated to treat inflammatory lesions of non-nodular moderate-to-severe acne vulgaris in patients ≥ 9 years of age.

Anticoagulation Decisions in Atrial Fibrillation

Using the Delphi method of arriving at a consensus among clinicians concerning for which patients with atrial fibrillation should oral anticoagulants be recommended, the risk of stroke, the risk of hemorrhage, and patient-specific factors emerged. Many of these factors are not included in the guidelines and should be studied further.

Treating Depression in Epilepsy: To Medicate or Not?

Epileptic patients with major depression were randomized to either cognitive behavioral therapy (CBT) or sertraline. Depression and related secondary health outcomes were analyzed in both groups. Sertraline and CBT were found to be equally efficacious with improvement in mood in more than half of patients.

Optimism Could Increase Odds of ‘Exceptional Longevity’

An analysis of 10-year follow-up data from the Nurses’ Health Study and 30-year follow-up data from the Veteran Affairs Normative Aging Study revealed a significant association between baseline levels of higher optimism and longevity, even when data were adjusted for health behaviors and psychosocial factors.

Does a Repeat Course of IVIg Help in Severe Guillain-Barré Syndrome?

In an open-label, non-randomized clinical trial using a second course of intravenous immunoglobulin (IVIg) to treat patients with Guillain-Barré syndrome, no benefit was observed. A single course of 2 g/kg of IVIg should be administered. No additional treatment is helpful.

Stereotactic Radiosurgery for the Treatment of Cerebral Cavernous Malformations

In this comprehensive review of studies comparing treatments for cerebral cavernous malformations, there were no randomized or blinded outcome trials, and the most effective treatment remains uncertain.