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REM Behavior Disorder as a Predictor of Parkinson’s Disease

Here are the results of a carefully executed study of REM behavior disorder patients compared to controls and those with Parkinson’s disease.

Increased Dietary Intake of Folate Reduces the Risk of Developing Alzheimer's Disease

An increased dietary intake of folate reduces the risk of developing AD.

Imaging Depression in Parkinson's Disease: Role of the Limbic System

Depression and anxiety in Parkinson's disease might be associated with a specific loss of dopamine and noradrenaline innervation in the limbic system.

Clipping vs Coiling for Ruptured Intracranial Aneurysms

In a randomized trial of neurosurgical clipping versus endovascular coiling for ruptured intracranial aneurysms, endovascular coiling was more likely to result in independent survival at 1 year.

Sleepwalking: More Often Neurological Than Psychiatric

Successful treatment of SDB, which is frequently associated with chronic sleepwalking, controlled the syndrome in young adults.

A Step Towards Restorative Therapy in Parkinson's Disease

Dopamine neuronal replacement cell therapy can be beneficial for patients with advanced disease, and that changing technical approaches could have a favorable impact on efficacy and adverse events following neural transplantation.

Review: HIV and Myopathy

Introduction of HAART has dramatically modified the natural history of HIV disease by controlling viral replication, but, in turn, lengthening of the survival of HIV-infected individuals has been associated with an increasing prevalence of iatrogenic conditions.

TIA Management: Emphasis on Urgent Evaluation and Treatment

Patients with transient ischemic attacks should usually be admitted to the hospital and receive rapid evaluation and treatment.

Parkinson's Disease with Camptocormia: A Central or Peripheral Etiology?

Camptocormia in PD is an extreme forward flexion of the spine, and has many characteristics of an axial action dystonia. The contribution of myopathy in muscles responsible for trunk extension has yet to be determined, and may be secondary to the dystonia itself.

Pharmacology Watch

In response to several high-profile drug misadventures including the rofecoxib (Vioxx^®) withdrawal from the market, the FDA's Center for Drug Evaluation and Research (CDER) asked the Institute of Medicine (IOM) to assess the drug safety system in the United States.