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The virtues of a firm mattress are generally espoused by the medical and lay community alike despite the utter lack of scientific evidence to support it. In an attempt to shed light on this poorly understood subject, Kovacs and associates assess the effect of the firmness of a mattress on low back pain.
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Thirty-three consecutive patients with l3 or l4 radiculopathy were compared to 19 controls of comparable age to determine the best method for detecting quadriceps weakness in the office setting.
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In this randomized, placebo-controlled trial, 667 patients with stable advanced multiple sclerosis were assigned to 1 of 3 groups: oral cannabis, oral tetrahydrocannabinol, or placebo.
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New alternative anticoagulants now exist that may be equally efficacious as warfarin and allow a more convenient fixed dosing schedule with a superior safety profile.
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The diagnosis of amyotrophic lateral sclerosis (ALS) at an early stage can be difficult. It is desirable to have an accurate diagnostic test due to the prognosis of the illness, as well as the potential ability to treat patients earlier.
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Fifty-one consecutive hepatitis c patients with neuropathy were evaluated to determine whether, and by what mechanism, cryoglobulinemia was associated with peripheral neuropathy.
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Benbadis and associates reviewed the medication history of patients with EEG-confirmed idiopathic generalized epilepsy.
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In this elegant study, Seif and colleagues asked a simple question: does DBS alter urodynamic parameters in patients with Parkinson's disease?
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Relying on careful monitoring to reduce the risk of toxicity, Ritchie and colleagues carried out a 36-week phase II test of the efficacy of clioquinol in reducing plasma beta-amyloid levels and slowing cognitive decline in patients with moderately severe Alzheimer's disease.
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In contrast to arterial thrombo-embolic ischemic stroke, cerebral venous sinus thrombosis (CVST) is unique in its clinical presentation and treatment algorithm. As reported by Ferro and associates on behalf of the multicenter international ISCVT study, venous stroke, typically treated with heparin, has a good outcome in the vast majority of cases.
