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A once-a-day dose of a valacyclovir reduces the rate of transmission of genital herpes (HSV-2) from an infected partner to an uninfected susceptible partner, according to a new study.
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Stiell and associates, convinced that the National Emergency X-Radiology Utilization Study Low-Risk Criteria rule leads to unnecessary testing and delayed triage of patients in the ED, developed the Canadian C-Spine Rule to assess alert, stable patients for traumatic cervical spine injury.
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Fourteen consecutive patients with sciatica were enrolled in this open-label trial of lamotrigine to determine its efficacy in pain control and its dose response curve.
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There are considerable anecdotal data suggesting that melatonin may improve sleep. Singer and colleagues carried out a trial of 2 sustained-release doses of melatoninone moderately high dose of 10 mg and one moderately low dose of 2.5 mg.
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Munger and colleagues reviewed a database of 187,563 women enrolled in the Nurses Health Study, which longitudinally surveyed participants aged 25-55. There were 173 women with probable or definite multiple sclerosis (MS). Vitamin D intake was determined through the study questionnaire and 4 1-week diet records.
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The possible association of migraine and stroke remains an active area of controversy in clinical neurology. Since migraines predominantly affect young people and the medications used can cause vasoconstriction, assessing the full vascular risk profile of migraine is important from a diagnostic and therapeutic point of view. To date, the literature is incomplete.
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New guidelines for the treatment of bacterial rhinosinusitis were published in the January supplement of Otolaryngology-Head and Neck Surgery by the Sinus and Allergy Health Partnership.
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The concept that epilepsy arises from an imbalance between excitatory and inhibitory influences in epileptogenic tissue has become fundamental to further investigations of the pathophysiology of this disorder. The primary observation motivating the study of Eid and colleagues is that glutamate levels are elevated in patients with mesial temporal sclerosis (MTS), perhaps the most common cause of medication-resistant epilepsy.
