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Treatment for McArdle’s Disease
In this simple yet elegant, single-blind, placebo-controlled, crossover study, 12 patients with McArdles disease were given a sucrose, or artificially sweetened placebo load, prior to aerobic exercise to determine if this might improve exercise tolerance. Average age of the 7 men and 5 women was 37 years, and all had lifelong exercise intolerance, episodic muscle cramps, and myoglobinuria triggered by exercise. -
Clinical Briefs in Primary Care Supplement