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It seems prudent to strongly consider use of melatonin in our cognitively delayed patients with disordered sleep, but to monitor those with epilepsy very closely for exacerbation, and withdraw the drug.
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These studies provide additional data about the higher risk of relapse, and the greater potential for progression of disability following childbirth.
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Absence of evidence-based medicine is both humbling, as well as a reminder of how substantial a role the art and oral tradition of medicine plays in the care of neurologic patients.
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Methylprednisolone significantly improves the recovery of peripheral vestibular function in patients with vestibular neuritis, whereas valacyclovir does not.
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The MATCH data provide quite strong evidence that the clopidogrel-aspirin combination is a less favorable option than previously thought, but its use may not be completely contraindicated.
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The means by which prions cause neuropathologic damage remains to be established.
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This condition preferentially affects large myelinated fibers of the posterior roots, may respond favorably to treatment, and may be a restricted form of chronic inflammatory demyelinating polyradiculoneuropathy.
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Current clinical trial evidence favors the use of aspirin or clopidogrel as first-line agents for the majority of patients with vascular disease.
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The first head-to-head comparison study of an ACE inhibitor and an angiotensin receptor blocker, to assess renoprotective effects in type 2 diabetes, has shown that the drugs are comparable in their benefit.
