Internal Medicine
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Does a Gluten-free Diet Lower the Risk of Coronary Artery Disease in Adults?
A prospective, cohort study of health professionals conducted over 24 years revealed no significant association between long-term consumption of gluten and the risk of coronary artery disease in both adult men and women with no history of coronary artery disease.
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Recent Advances in Sleep Medicine
This article reviews recently published research on sleep medicine. -
Primary Headaches: Look, Listen, and Diagnose Rather Than Image
SYNOPSIS: The diagnosis of primary headache disorders by a computerized and clinical paradigm can predict a baseline prevalence of intracranial abnormalities on brain imaging. Some historical “red flags” in children with headaches, including morning headaches and occipital pain, are not associated with increased intracranial abnormalities.
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Cerebellar Atrophy May Contribute to Cognitive Impairment in FTD
In this cross-sectional study, researchers identified distinct patterns of cerebellar atrophy and its association with cognitive dysfunction in the frontotemporal dementia syndromes.
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Ibudilast Shows Promise for the Treatment of Progressive MS
A Phase II trial of ibudilast in progressive multiple sclerosis demonstrated a decreased rate of brain atrophy when compared to placebo.
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Steroid Treatment Regimens for Chronic Inflammatory Demyelinating Polyneuropathy
In the United States, first-line treatment for chronic inflammatory demyelinating polyneuropathy (CIDP) is intravenous immunoglobulin (IVIG). Authors of this retrospective survey from Europe found that corticosteroid treatment had similar efficacy as IVIG and should be considered as first-line therapy for CIDP.
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Use of a Low-carbohydrate, Ketogenic Diet to Treat Obesity
Overweight and obesity have reached epidemic proportions in the United States. For individuals affected by obesity, clinical studies have shown that carbohydrate restriction, including a low-carbohydrate, ketogenic diet, can be a safe and effective treatment. This article includes a narrative review of clinical research studies and a practical description of implementing a “keto” diet for obesity.
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MRI for Patients With Pacemakers and Defibrillators
Performing an MRI on patients with pacemakers and defibrillators that were not MRI-conditional was not associated with any clinically significant changes in device parameters.
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Clinical Context and Outcomes in Stress Cardiomyopathy
An analysis of the International Takotsubo Registry showed that long-term mortality is similar to that observed in patients with acute coronary syndromes but varies widely depending on the triggering event.
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Tafamidis Improves Survival in Transthyretin Cardiac Amyloidosis
Treatment with tafamidis in transthyretin amyloid cardiomyopathy patients produced reductions in all-cause mortality and cardiovascular hospitalizations. This was the first medical therapy to demonstrate improved survival for patients with this condition.