Internal Medicine
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Should Aspirin Be Used for Primary Prevention of Cardiovascular Events?
Primary prevention of cardiovascular disease and death by using daily low-dose aspirin is not recommended and should be reserved for those instances in which secondary prevention has been demonstrated to be effective in randomized clinical trials.
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Ultraearly Intravenous Thrombolysis for Acute Ischemic Stroke
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Thrombolysis for ‘Wake-up’ Stroke
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Costs and Consequences of Chronic Pain Among U.S. Adults
Chronic and disabling pain is a common and serious cause of morbidity among U.S. adults.
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Quality of Life After Focused Ultrasound Thalamotomy in Parkinson’s Disease
Mood, cognitive, and behavioral changes in tremor-predominant Parkinson’s disease patients, three and 12 months after receiving MRI-guided focused ultrasound thalamotomy, were correlated with quality of life more than the severity of tremor reduction.
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Effect of Diet on Hippocampal Volume in a Population at Risk for Alzheimer’s Disease
Magnetic resonance imaging of the brain in community-dwelling people (average age of 60 years) found that a long-term, high-quality diet was associated with larger hippocampal volumes after an average interval of 11 years.
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Is it Guillain-Barré or Acute-onset CIDP?
Acute inflammatory demyelinating polyneuropathy and acute-onset chronic inflammatory demyelinating polyneuropathy (CIDP) may present with identical clinical pictures and can be differentiated only with the passage of time. CIDP will have a slower course of progression and may involve relapses.
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Telemedicine Improves Outcomes in Heart Failure
In patients with chronic heart failure, adding a remote patient management program to usual care was associated with improvement in unplanned cardiovascular hospitalization or death.
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Total Arterial Revascularization: Where Is It?
The results of a long-term follow-up study of matched pairs of patients undergoing surgical coronary artery revascularization showed that total arterial graft usage significantly reduced all-cause mortality vs. left internal mammary artery plus saphenous vein grafts.
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VEST: A Positively Negative Clinical Trial
In a randomized trial of the wearable cardioverter-defibrillator prescribed to patients with left ventricular dysfunction after acute myocardial infarction, overall compliance rates were low. The authors observed no significant improvement in arrhythmic death rates; yet, overall mortality was lower.