Internal Medicine
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Thrombolysis for ‘Wake-up’ Stroke
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Costs and Consequences of Chronic Pain Among U.S. Adults
Chronic and disabling pain is a common and serious cause of morbidity among U.S. adults.
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Quality of Life After Focused Ultrasound Thalamotomy in Parkinson’s Disease
Mood, cognitive, and behavioral changes in tremor-predominant Parkinson’s disease patients, three and 12 months after receiving MRI-guided focused ultrasound thalamotomy, were correlated with quality of life more than the severity of tremor reduction.
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Effect of Diet on Hippocampal Volume in a Population at Risk for Alzheimer’s Disease
Magnetic resonance imaging of the brain in community-dwelling people (average age of 60 years) found that a long-term, high-quality diet was associated with larger hippocampal volumes after an average interval of 11 years.
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Is it Guillain-Barré or Acute-onset CIDP?
Acute inflammatory demyelinating polyneuropathy and acute-onset chronic inflammatory demyelinating polyneuropathy (CIDP) may present with identical clinical pictures and can be differentiated only with the passage of time. CIDP will have a slower course of progression and may involve relapses.
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Telemedicine Improves Outcomes in Heart Failure
In patients with chronic heart failure, adding a remote patient management program to usual care was associated with improvement in unplanned cardiovascular hospitalization or death.
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Total Arterial Revascularization: Where Is It?
The results of a long-term follow-up study of matched pairs of patients undergoing surgical coronary artery revascularization showed that total arterial graft usage significantly reduced all-cause mortality vs. left internal mammary artery plus saphenous vein grafts.
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VEST: A Positively Negative Clinical Trial
In a randomized trial of the wearable cardioverter-defibrillator prescribed to patients with left ventricular dysfunction after acute myocardial infarction, overall compliance rates were low. The authors observed no significant improvement in arrhythmic death rates; yet, overall mortality was lower.
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LDL Cholesterol: How Low Do We Go?
A meta-analysis of 29 cholesterol-lowering outcome studies with baseline average low-density lipoprotein (LDL) cholesterol levels ≤ 70 mg/dL showed consistent major adverse cardiovascular event risk reductions down to average LDL levels of 21 mg/dL without any increase in adverse events.
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MitraClip Scores Big Win in COAPT
The largest trial to date of MitraClip in highly selected patients with congestive heart failure and functional mitral regurgitation revealed significant reductions in heart failure hospitalization and two-year mortality.