Internal Medicine
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Initial Management of Patients With Medication-overuse Headache
As part of a randomized treatment trial for medication-overuse headache, a simple protocol that provided early advice on stopping excessive medications was effective in one-third of patients, even before any prophylactic medications were started.
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Clinicians Prescribe Antibiotics for Excessive Duration in Patients With a Diagnosis of Acute Sinusitis
Clinicians inappropriately prescribe antibiotics most often to patients with a diagnosis of acute sinusitis for durations much longer than recommended.
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Canagliflozin Reduces Risk of Heart Failure Hospitalizations for Diabetic Patients
In type 2 diabetes mellitus patients with a higher risk of cardiovascular disease, canagliflozin lowered the risk of cardiovascular death or heart failure hospitalization. Patients with pre-existing heart failure may experience even greater benefit.
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Substance Abuse and Myocardial Infarction
Among patients ≤ 50 years of age with first myocardial infarctions, use of cocaine or marijuana increased the likelihood of an ST-segment elevation myocardial infarction and the subsequent risk of all-cause and cardiovascular mortality.
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Vitamin C for Postoperative Atrial Fibrillation Risk
The authors of a systematic review of 13 studies found convincing evidence that vitamin C supplementation, beginning before cardiac surgery and continuing for a few days postoperatively, can decrease the risk of atrial fibrillation.
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Tele-yoga for Chronic Pain: A Management Therapy for the Future?
Researchers reviewed the use of yoga instruction, transmitted remotely for access-challenged patients in treating chronic pain. The study suggests that tele-yoga can be an effective treatment, but it is unknown if it is as effective as in-person yoga instruction.
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B Vitamins and Hip Fracture Risk: To B or Not to B?
Researchers conducted a secondary analysis and extended follow-up of two large, randomized, controlled trials to show the relationship between supplementing with B vitamins and the incidence of hip fractures.
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Chicken or Egg: Does Improving Sleep Improve Mental Health?
Authors of this large, randomized, controlled study strongly suggest that better sleep leads to improvement in several areas of mental health, and that a digital form of cognitive behavior therapy can significantly help in treatment of insomnia.
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Aerobic Exercise and Heart Health: Is It Ever Too Late to Start?
In this prospective, randomized, controlled trial, researchers demonstrated improvements in exercise tolerance and diastolic cardiac function in middle-aged, healthy, sedentary men and women performing intensive aerobic exercise over a two-year period.
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Dual Antiplatelet Therapy for Acute Ischemic Stroke and TIA