Infectious Disease
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Preparing for Avian Influenza
Although human-to-human transmission has not been observed for avian influenza in the United States at this time, and the situation is seen only as a possibility, it is important that all emergency care providers understand the virus and its potential implications for both practice and patients.
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Gepotidacin Tablets (Blujepa)
The U.S. Food and Drug Administration has approved gepotidacin, a first-in-class antibacterial medication for the treatment of uncomplicated urinary tract infections.
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Infectious Disease Updates
Old Habits Die Hard, Especially with TB; Paxlovid: Is It Still Worth the Cost?
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Career Satisfaction and the Unmet Need for Infectious Disease Clinicians
There is a shortage of physicians in the United States, and many current physicians are considering reducing or ending their current clinical practices. Leading risk factors for discontinuing clinical work are taking fewer than 15 days of vacation each year, continuing to respond to electronic medical record inbox messages during vacation, and working more than 30 minutes per day during vacation.
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Moldy Bloodstream Infections
Bloodstream infections due to molds are uncommon, occurring predominantly in association with severe immunocompromise, even in the presence of anti-mold prophylaxis.
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Preventing Respiratory Syncytial Virus Illness in Infants
Prevention of respiratory syncytial virus (RSV) illness by using a monoclonal antibody, nirsevimab, in young infants entering the winter RSV season was recommended in 2023. Subsequently, effectiveness was evaluated in children in the northeastern United States. Nirsevimab was 68% effective in preventing RSV-associated need for medical care and 81% effective in preventing hospitalization for RSV-related illness.
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Antibiotics for Asymptomatic Bacteriuria: Using Urinalysis to Improve Stewardship
A cohort study found that in patients receiving antibiotics for a urinary tract infection, a urinalysis with pyuria and/or nitrituria identified 40% more cases of unnecessary antibiotic use compared to asymptomatic bacteriuria.
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Aztreonam and Avibactam for Injection (Emblaveo)
The U.S. Food and Drug Administration has approved a new combination antibiotic for the treatment of complicated intra-abdominal infections where there are limited or no alternative options.
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Death Due to the ‘No Name’ Virus in Santa Fe
On Feb. 26, 2025, it was announced that the bodies of actor Gene Hackman and his wife and caregiver Betsy Arakawa had been found in their Santa Fe, NM, home
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Bacterial Vaginosis: Treat the Man, Too
In a randomized trial, treatment of the regular male partner with oral and topical agents was strongly associated with a reduced risk of recurrence of bacterial vaginosis in the female partner.