Infectious Disease
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Staphylococcus aureus Endocarditis: A Selection of Just-Published Studies
A selection of reports published in the last two months cover microbiologic diagnosis and management issues.
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Paxlovid: Is It Still Worth the Cost?
Paxlovid is one of the most effective antivirals developed during the COVID-19 years, demonstrating significant reductions in hospitalization and death in higher-risk persons, as well as the time to viral elimination. However, it does not shorten the duration of symptoms, and there is little evidence that Paxlovid reduces the risk of developing long COVID symptoms.
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Antibiotics for Asymptomatic Bacteriuria: Using Urinalysis to Improve Stewardship
A cohort study found that in patients receiving antibiotics for a urinary tract infection, a urinalysis with pyuria and/or nitrituria identified 40% more cases of unnecessary antibiotic use compared to asymptomatic bacteriuria.
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Preventing Sexually Transmitted Infections Has Just Gotten Much Harder
The national sexually transmitted infections (STIs) lab that was recently closed by the federal government had been working on drug-resistant gonorrhea, collecting samples, developing new laboratory diagnostic tests, and monitoring antimicrobial resistance.
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Effects of Federal Cuts to STI Programs Could Be Significant
Some sexually transmitted infections (STIs) have risen dramatically since the COVID-19 pandemic. But the hope was that public health clinics’ increased screening and treatment and public awareness campaigns eventually would lead to a decrease in STIs.
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Preparing for Avian Influenza
Although human-to-human transmission has not been observed for avian influenza in the United States at this time, and the situation is seen only as a possibility, it is important that all emergency care providers understand the virus and its potential implications for both practice and patients.
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Gepotidacin Tablets (Blujepa)
The U.S. Food and Drug Administration has approved gepotidacin, a first-in-class antibacterial medication for the treatment of uncomplicated urinary tract infections.
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Infectious Disease Updates
Old Habits Die Hard, Especially with TB; Paxlovid: Is It Still Worth the Cost?
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Career Satisfaction and the Unmet Need for Infectious Disease Clinicians
There is a shortage of physicians in the United States, and many current physicians are considering reducing or ending their current clinical practices. Leading risk factors for discontinuing clinical work are taking fewer than 15 days of vacation each year, continuing to respond to electronic medical record inbox messages during vacation, and working more than 30 minutes per day during vacation.
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Moldy Bloodstream Infections
Bloodstream infections due to molds are uncommon, occurring predominantly in association with severe immunocompromise, even in the presence of anti-mold prophylaxis.