Infectious Disease
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Bad to the Bone: Huge TB Outbreak Traced to One Donor
A massive Mycobacterium tuberculosis outbreak spread to 81 bone tissue recipients in 20 states, leading to multiple patient deaths and 73 latent infections in healthcare workers, investigators with the Centers for Disease Control and Prevention (CDC) report.
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OSHA Urged to Break with CDC in Finalizing COVID-19 Regulation
Despite pleas for flexibility by infection control groups, the Occupational Safety and Health Administration is being urged by one of its more prominent former directors to adopt a tough standard that emphasizes airborne precautions to protect healthcare workers from COVID-19.
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Too Many Antibiotics May Affect Vaccine Response Among Infants, Toddlers
Remain cautious about overprescribing antibiotics.
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Etafilcon A Drug-Eluting Contact Lens with Ketotifen (Acuvue Theravision with Ketotifen)
Ketotifen-eluting contact lens can be prescribed to correct refractive ametropia (myopia and hyperopia) for phakic or aphakic patients who wear suitable lens and experience ocular itch caused by allergic conjunctivitis.
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Women at Higher Risk for Intracranial Aneurysm Ruptures
Women with ruptured aneurysms were older than men, were less often smokers, and more often experienced internal carotid artery aneurysms. They also tended to produce larger-sized aneurysms than men.
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Men More Likely to Produce High-Risk, Dangerous Carotid Artery Plaques
Investigators found significant differences in mean total plaque volume between men and women. Men were more likely to experience intraplaque hemorrhage and produce lipid-rich necrotic cores with coexistence of calcifications. Men also were more likely to exhibit thin or ruptured fibrous caps or ulcerations in their atherosclerotic plaques.
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Pregnant, Influenza-Infected, and Hospitalized
Almost one-third of women age 15-44 years hospitalized with influenza were pregnant and almost 5% required intensive care.
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Weight Loss and Other Interventions to Alleviate Obstructive Sleep Apnea
Obesity is a primary cause of obstructive sleep apnea (OSA), and improvements in weight and other lifestyle factors can yield benefits for OSA and related comorbidities.
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Extend Life Expectancy by Achieving Type 2 Diabetes Therapeutic Goals
Investigators analyzed gains in life expectancy by achieving treatment goals, finding significant gains from lower body mass index, glycated hemoglobin, systolic blood pressure, and low-density lipoprotein cholesterol.
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Updated Aspirin Guidance from the U.S. Preventive Services Task Force
The authors of new recommendations advise avoiding initiating aspirin for primary prevention of cardiovascular disease in adults age 60 years or older, individualizing decisions based on characteristics and preferences for patients.