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Maribavir (Livtencity)

The FDA approved maribavir as the first drug to treat adult and pediatric patients with post-transplant cytomegalovirus infections that do not respond to currently available antiviral treatment.

Persistent Inflammation and Post-COVID Syndrome

Ongoing inflammation may contribute to long COVID.

Immunosuppressants and the Risk for Clostridioides difficile Infection

A retrospective cohort study found that for patients taking immunosuppressing medications, the greatest risk for C. difficile infection occurred for those receiving calcineurin inhibitors and those taking drugs from multiple immunosuppressant classes.

Aminoglycoside-Induced Ototoxicity: Test Before You Treat?

Mitochondrially inherited, aminoglycoside-induced ototoxicity can cause irreversible hearing loss. Approximately 0.2% of the population is at risk, and new point-of-care genetic testing could prompt avoidance of aminoglycoside use without undue delay in antibiotic administration.

Midlines vs. Peripherally Inserted Central Venous Catheters

Midline catheters are, at a minimum, at least as safe or safer than peripherally inserted central catheters for durations of at least 14 days, thus offering an effective alternative for venous access.

Donepezil Transdermal Patch (Adlarity)

Donepezil transdermal system can be prescribed to treat mild, moderate, and severe dementia of the Alzheimer’s type.

Bloodstream Infections During COVID-19

Severity of illness, prolonged hospital stays, use of mechanical ventilation, and use of immune-modulating agents in patients with COVID-19 may have contributed to observed increases in hospital-acquired blood stream infections and attendant mortality.

Empower Patients With Education Resources About Pelvic Floor Disorders

Online patient resources for pelvic floor disorders on the American Urogynecologic Society patient portal are underused by women with pelvic floor disorders.

Gastrointestinal Bleeding on Anticoagulants: Predicting Colorectal Cancer in Afib Patients

A large Danish registry study showed that in atrial fibrillation patients on oral anticoagulants and who experience a lower gastrointestinal bleed, the incidence of a subsequent diagnosis of colorectal cancer is significantly higher than in those without bleeding.

The Effects of Diet, Nutrition, and Weight on Fibromyalgia

This review of evidence for the use of dietary interventions to treat fibromyalgia shows symptom reduction associated with a variety of healthy diets. Weight loss may be key to understanding this connection, but more research is needed.