Infectious Disease
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An Epic Battle: SARS-CoV-2 vs. the Human Immune System
Penny Moore, PhD, an HIV researcher for about two decades, has redeployed much of her research to measure humoral immune response to SARS-CoV-2 infection and vaccination.
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WHO Cooperative Treaty for Next Pandemic Begins in Controversy
The World Health Organization is continuing discussions of an international treaty or framework for global cooperation during the next pandemic, but the effort may struggle to gain traction in a divided, highly politicized environment currently holding sway in the United States.
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Monkeypox Countermeasures Include Vaccines, PEP, and Antiviral Treatment
Although monkeypox cases are expected to increase as a result of the national call to clinicians to identify cases, the United States has no surfeit of medical countermeasures. These include two vaccines, a vaccinia immune globulin intravenous product, an antiviral drug, and large testing capacity.
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Special Report: Monkeypox Spread to 29 Non-Endemic Nations Unprecedented
The near-simultaneous emergence of monkeypox in the United States, Europe, and other regions where it rarely is seen has raised questions whether the virus could become endemic beyond West and Central Africa, where outbreaks are more common.
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Mavacamten Capsules (Camzyos)
Mavacamten can be prescribed to adults with symptomatic New York Heart Association class II-III obstructive hypertrophic cardiomyopathy to improve functional capacity and symptoms.
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HPV Vaccination in Adolescence Prevents Cancer More than 10 Years Later
In a study of human papillomavirus (HPV) vaccination, researchers evaluated cancer protection over up to 11 years of follow-up. During this time, the authors noted 100% vaccine efficacy at preventing HPV-associated cancers.
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Regarding Exercise Capacity Past Age 75 Years, What Is Normal?
A group of researchers delivered results that could help inform clinicians about the expected exercise test performance of older patients.
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Recommendations Regarding Physical Activity to Delay Death
Using objective measurements of exercise intensity, researchers approximated 110,000 U.S. deaths/year could be prevented by a 10-minute daily increase in moderate-to-vigorous physical activity in adults age 40-85 years.
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Beware the Cardiovascular Risks Associated with Thyroid Hormone Replacement Therapy
Thyroid levels outside the euthyroid range have been associated with higher cardiovascular risk in patients taking thyroid hormone to treat hypothyroidism. In this study, a higher cardiovascular mortality rate was associated with exogenous hyperthyroidism and exogenous hypothyroidism.
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Long COVID Patients Report Symptoms 15 Months Later
Brain fog, dizziness, and more side effects can linger for many months after initial SARS-CoV-2 infection.