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Novavax COVID-19 Vaccine, Adjuvanted (NVX-CoV2373)

Novavax is authorized to be administered to patients age 18 years and older for active immunization to prevent COVID-19 caused by SARS-CoV-2.

COVID-19 Rebound

Symptomatic and virologic recrudescence after treatment of patients with COVID-19 with Paxlovid occurs in a tiny percentage of patients and generally is mild and self-limited.

COVID-19: Duration of Shedding of Transmissible Virus

Patients with COVID-19 were found, by culture, to shed replication-competent virus after an initial PCR test for median durations of four to five days.

New Details Emerge About Acute Flaccid Myelitis, Cases Could Surge This Year

Researchers uncovered evidence indicating enterovirus D68 directly infects neurons in the spinal cord, prompting an immune response that leads to the limb weakness that is characteristic of acute flaccid myelitis. Investigators shed important light on the disease process that takes place in children who develop this polio-like illness. This is progress that can help lead to better treatments.

Text Messages Boosted Pediatric Flu Vaccination Rates

Personalized, interactive, educational reminders led parents to bring children for the second shot faster and at a higher rate.

Outcomes of COVID-19-Associated Acute Myocarditis

In a review of COVID-19-associated acute myocarditis, investigators learned it is a rare complication that can occur without concomitant pneumonia, and frequently presents as cardiogenic shock. With supportive therapy, the short-term mortality rate is low.

EPA, FDA Partner on Safer Medical Device Sterilization

Agencies seek cuts to ethylene oxide emissions, safe alternatives.

Infectious Disease Alert Updates

Remaining Questions in Syphilis Treatment; The Great Imitator Imitates Again

Molecular Test Panel Use for Children with Possible Meningitis

In children thought to have meningitis, the use of a molecular test pathogen panel reduced the time to optimal antimicrobial use and reduced the duration of intravenous antibiotic use. However, there was no difference in the time to effective antimicrobial administration or the length of hospital stay between those with treatable pathogens who were and were not evaluated using molecular testing.

Outbreaks of Infectious Enteritis in the United States: Norovirus Wins Again

More than 1 million people acquired enteric infections in the course of almost 40,000 outbreaks in the United States over the 11 years of this study.