Browse Infectious Disease Articles by Topic

Rehospitalization Common in Herpes Encephalitis

Herpes simplex encephalitis (HSE) is the most common cause of infectious encephalitis in the United States, accounting for around 30% of all causes of infectious encephalitis in the United States. With the advent of antiviral therapy and improved diagnostic measures, mortality and morbidity have improved over the past few decades, but patients remain at risk for long-term neurologic sequelae and even relapse.

U.S. Endemic Fungal Infection Surveillance

In the United States in 2019, 29,061 cases of coccidioidomycosis were reported, as were 1,124 cases of histoplasmosis and 240 of blastomycosis.

CDC Warning: Enterovirus-D68 Re-Emerging and Once Again Raising the Specter of Acute Flaccid Myelitis in Children

The Centers for Disease Control and Prevention is receiving increasing reports of pediatric infections with enterovirus-D68, which previously has been associated with the development of acute flaccid myelitis.

Safety of Infliximab After Live Vaccines

Despite concerns about the use of infliximab for children with Kawasaki disease shortly after administration of live vaccines, retrospective reviews do not show any vaccine-related infections following subsequent infliximab use.

Doxycycline Plus a Beta-Lactam for Treatment of Inpatients with Community-Acquired Pneumonia

In this retrospective study of an elderly male population hospitalized with community-acquired pneumonia, the combination of doxycycline with a beta-lactam was at least as effective as a respiratory fluoroquinolone or a combination of a beta-lactam with azithromycin.

Cellular Tests Are Not Accurate for Diagnosing Lyme Disease

A prospective case-control study from the Netherlands evaluated three cellular tests for diagnosing Lyme disease. All three had low specificity compared to serological testing, leading to an unacceptably high number of false-positive results.

Boosting with the New Bivalent COVID-19 Vaccines

The Centers for Disease Control and Prevention has made recommendations for the use of the newly approved bivalent COVID-19 booster vaccine.

Antibiotic Resistance: We Were Doing Great and then COVID Happened

After improvement, antimicrobial resistance in the United States significantly increased.

Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD

This multicenter cohort study revealed a high incidence of PTSD symptoms among family members of COVID-19 patients at three months after the ICU admission.

Remaining Questions in Syphilis Treatment

Eight leading experts on sexually transmitted diseases convened to discuss key questions in the management of syphilis in adults with and without HIV infection based on a systematic review of the literature. More than 3,000 articles were screened, and the discussion focused on 95 relevant publications and three main topics.