Infectious Disease
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COVID-19 Rebound: To Retreat or to Re-Treat
Re-treatment of non-immunocompromised patients with mild-moderate COVID-19 rebound with nirmatrelvir/ritonavir provided no significant benefit.
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Current Recommendations for Childhood Respiratory Vaccines
Amidst prevalent vaccine hesitancy, changing governmental advisory groups, and altered recommendations, COVID immunization still is recommended for all children aged 6 through 23 months and for older children with medical risk factors.
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Pertussis: Concerning News from Mexico, Brazil, and China
Related to under-immunization of pregnant women and children, pertussis is spreading in several countries within the Americas. Macrolide resistance of Bordetella pertussis is now common in China.
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Preventing SARS-CoV-2 Infection with an Allergy Nasal Spray
Use of the antihistamine azelastine nasal spray was effective in preventing SARS-CoV-2 infection in young, healthy, vaccinated outpatients.
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The Health and Economic Burden of Long COVID in the United States
Researchers using a computational simulation model found that the current health and economic burden of long COVID already exceeds the cost of several chronic diseases and will continue to grow as COVID-19 cases increase.
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Community-Acquired Pneumonia Guidelines: Updates and Disputes
An update of elements of community-acquired pneumonia guidelines has been published. Of note is that these were not endorsed by the Infectious Diseases Society of America because of disagreement over recommendations for empiric antibiotic administration to some patient subsets with positive tests for respiratory viral infection.
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Fever in the Child Returning from Global Travel
Every year, a significant number of families travel internationally with children, who then have a high rate of febrile illness after returning home. While most travel-acquired infections are self-limited and mild, some diseases may rapidly become fatal, and early recognition and aggressive management can maximize the child’s outcome. This review presents a focused clinical approach to caring for a child returning from international travel with a fever.
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Infectious Disease Updates
Visceral Larva Migrans from Baylisascariasis; Measles Testing of Persons with HIV; Ambulatory Glucose Monitoring a Risk for Bloodborne Pathogens
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Fleas, Typhus, and Texas
Cases of flea-borne typhus are dramatically increasing in Texas.
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Pertussis: Concerning News from Mexico, Brazil, and China
Related to under-immunization of pregnant women and children, pertussis is spreading in several countries within the Americas. Macrolide resistance of Bordetella pertussis is now common in China.