Infectious Disease
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A Novel Rifabutin-Containing Combination Regimen Is Effective for Eradicating H. pylori Infection
A Phase III, randomized, controlled trial found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.
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Respiratory Syncytial Virus — Effective Prevention Still Needed
Prevention of respiratory syncytial virus infection is needed but challenging. New studies show some favorable effectiveness on infant outcomes with both vaccination of healthy pregnant women and passive single-dose immunization of prematurely born babies.
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Repeat Infections with Endemic Coronaviruses and Possible Implications for COVID-19
Repeat infection with endemic seasonal coronavirus occurs commonly and raises concerns about immunity to SARS-CoV-2 as well as about the efficacy of vaccines in the protection against infection due to this virus.
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Dexamethasone for COVID-19 Inpatients Requiring Oxygen
Dexamethasone administration is associated with reduced 28-day mortality in oxygen-requiring COVID-19 patients, including those receiving mechanical ventilation.
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The COVID-19 Pandemic: What Comes Next? Lessons from Seasonal Coronaviruses
In temperate regions other than China, human seasonal coronaviruses circulate most heavily during the winter months, overlapping with influenza and respiratory syncytial virus — and this may be the eventual pattern for SARS-CoV-2.
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Decitabine and Cedazuridine Tablets (Inqovi)
Inqovi should be prescribed to treat adults with myelodysplastic syndromes.
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Cheyne-Stokes Respiration in Heart Failure
A comprehensive cardiorespiratory study of stable systolic heart failure patients showed Cheyne-Stokes breathing in the awake, upright position is related to hypercapnia and is independently associated with a higher risk of cardiac death.
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Risks of Hookah Smoking
An average hookah contains as much tobacco as 20 filtered cigarettes. The nicotine hit from a hookah is every bit as real and as addictive as smoking cigarettes. The temperature of the smoke when heated electronically in newer hookahs, rather than by older charcoal versions, may be cidal to lung cells.
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Stroke Risk: COVID-19 vs. Influenza
During the early surge in COVID-19 infections in New York City, many neurologists observed an unusual frequency of ischemic stroke. Researchers investigated further. Read on to learn what they discovered.
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The Relationship Among Step Count, Step Intensity, and Mortality in Adults
Investigators found an association between higher number of steps taken daily and lower all-cause mortality, lower mortality from cardiovascular disease, and lower mortality from cancer, but no association between intensity of steps and mortality in any of those areas.