Infectious Disease
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Antibiotic Stewardship: Who’s Responsible?
A joint Pew/AMA survey about resistance and prescribing habits sheds light on provider attitudes and the work ahead.
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Congress Considers Legislation Addressing Healthcare Provider Mental Health
The COVID-19 pandemic has placed historic burdens on already-taxed frontline clinicians.
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High Lateral Infarction, or Something Else?
The ECG in the figure was obtained from a man with new onset palpitations. What is the probable cause of his symptoms? Is there high lateral infarction, or is something else accounting for the Q waves in leads I and aVL?
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Fostemsavir Extended-Release Tablets (Rukobia)
Fostemsavir is indicated, with other antiretrovirals, to treat HIV-1 infections in heavily treatment-experienced adults with multidrug-resistant HIV-1 infections who are failing current regimens.
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COVID-19 and Steroids: Is There a Consensus?
A study of adults admitted with COVID-19 pneumonia revealed risk factors associated with developing acute respiratory distress syndrome (ARDS) and progression from ARDS to death included older age, neutrophilia, organ dysfunction, and coagulation derangement.
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Inappropriately Broad Empiric Antibiotics, Higher Mortality, and Community-Onset Sepsis
A retrospective cohort study revealed broad-spectrum antibiotics were unnecessarily prescribed to patients with community-onset sepsis and were associated with worse outcomes and higher mortality.
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Thin Evidence Supporting the Obesity Paradox in STEMI
This largest-to-date analysis of six randomized studies of ST-elevation myocardial infarction revealed no association between body mass index and infarct size, one-year mortality, or heart failure hospitalization.
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Study: No Relationship Between Blood Type, COVID-19 Severity
But those with certain blood types may be at higher risk for testing positive.
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Infectious Disease Alert Updates
Metronidazole Neurotoxicity Is Real; 2020 Updated LTBI Treatment Guidelines; Risks of Hookah Smoking
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A New Treatment for Recurrent Bacterial Vaginosis?
In this randomized controlled trial of 228 women, Lactobacillus crispatus CTV-05 (Lactin-V) applied vaginally for 11 weeks reduced the incidence of recurrent bacterial vaginosis from 45% in the placebo arm to 30% in the Lactin-V arm.