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Medication poisonings in children; rosuvastatin vs atorvastatin for atherosclerosis; saw palmetto for prostate symptoms; using atypical antipsychotics for off-label indications in adults; and FDA actions.
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Two recent clinical trials, rocket af and aristotle, have added two new direct thrombin inhibitors, in addition to dabigatran (RE-LY), to our armamentarium to prevent stroke in patients with atrial fibrillation.
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Cases of autopsy-proven corticobasal degeneration examined in a U.S. academic center presented with frontal-predominant behavioral or cognitive deficits, with a movement disorder following later in the majority.
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Progressive multifocal leukoencephalopathy is a rare complication of immunosupression in patients who undergo organ transplantation, with a high death rate.
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Fibroblast growth factor 21, an important regulator of glucose and lipid metabolism in muscle, is strikingly elevated in the serum of patients with mitochondrial respiratory chain deficiencies.
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Measurement of biomarkers, including Ab42 and tau protein in the CSF along with volumetric measurements of the hippocampus, may help in the diagnosis of early or presymptomatic Alzheimer's disease.
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Apixaban could soon join the anticoagulation market; Chinese herbs for flu; chronic medication and discontinuation after hospitalization; and FDA actions.
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Extended-release pramipexole is effective in both early and advanced Parkinson's disease, with a safety and tolerability profile similar to that of immediate-release pramipexole.
