Head Trauma
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Repeated Head Impacts Are Associated with Tau Astrogliopathy
This study demonstrates that both traumatic brain injury and participation in contact sports are independently associated with increased tau astrogliopathy, particularly thorn-shaped astrocytes, even when cases of chronic traumatic encephalopathy neuropathologic change are excluded.
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Post-Traumatic Headaches: Common and Complicated
The brain’s ability to modulate pain influences the development and persistence of post-traumatic headache (PTH). Functional magnetic resonance imaging (fMRI) studies in people with PTH show higher pain-induced brain activation in specific regions, such as the postcentral gyrus, superior temporal gyrus, and ventral striatum, as compared to healthy controls. Over 16 weeks of observation, progressive normalization in pain-induced brain activation was seen in the PTH group with headache improvement, with persistently elevated activation in the non-improvement PTH group.
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Repeated Head Trauma May Lead to Parkinsonism in Patients with CTE
Repeated head injury from years of contact sports play in men with confirmed chronic traumatic encephalopathy (CTE) may cause pathological changes in the substantia nigra that lead to parkinsonism in a subset of patients with CTE.
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Is Autologous Bone Marrow Cell Therapy a Potential Treatment for Traumatic Brain Injury?
This study proposes that autologous bone marrow mononuclear intravenous infusion for severe traumatic brain injury in children appears safe and potentially may be efficacious.
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Usefulness of the Physical Examination in the Concussed Patient
This article suggests that certain specific physical examination findings may be helpful in evaluating and monitoring patients with sports-related concussion using oculovestibular responses and balance tests.
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New Research Suggests Treating Traumatic Brain Injury as a Chronic Illness
The road to recovery might be longer than initially thought.
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Major Traumatic Brain Injury Can Raise Dementia Risk
Patients with brain bleeding and a long hospital stay were 1.5 times more likely to develop dementia compared to those with no injury.
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U.K., U.S. Research Groups Report Progress on Objective Concussion Test
Word that a saliva test can accurately identify whether an individual has sustained a concussion has created quite a buzz in recent weeks.
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Plasma Biomarker May Indicate When Athletes Can Return to Play After Concussion
A better understanding of these biomarkers may help improve health and safety of athletes.
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Neuropathology and Dementia in Football Players With CTE
The authors of a cross-sectional study involving analysis of data from the ongoing Understanding Neurologic Injury and Traumatic Encephalopathy (UNITE) study found that dementia is likely a result of neuropathologic changes associated with repetitive head injury as well as non-head trauma-associated vascular pathologic changes in patients with chronic traumatic encephalopathy.