Browse Head Trauma Articles by Topic

Salivary microRNA as Biomarker to Predict Prolonged Concussion Symptoms

In a prospective cohort study of pediatric patients, aged 7 to 21 years, diagnosed with concussion, salivary microRNAs were found to be a potential biomarker for predicting prolonged concussion symptoms.

TBI in Prodromal Parkinson’s Disease

This population-based study using Medicare data demonstrated that in the five years prior to diagnosis of Parkinson’s disease (PD), when compared with age-matched controls, those who were diagnosed with PD had a higher incidence of traumatic brain injury (TBI). The TBI was rated as mild and concussive and was most often related to falls.

Optimizing Brain Oxygen in Severe Traumatic Brain Injury

In a Phase II, single-blind, randomized, multicenter trial, the use of intraparenchymal brain tissue oxygenation monitoring reduced brain tissue hypoxia in patients with severe traumatic brain injury.

Childhood Head Trauma and Risk of Subsequent Diagnosis of Multiple Sclerosis

A large study that reviewed longitudinally collected data from the national Swedish Patient Register found that head trauma in adolescents was associated with an increased risk of subsequent diagnosis of multiple sclerosis.

Tau as a Biomarker of Acute and Chronic Traumatic Brain Injury

The ongoing search for reliable biomarkers of traumatic brain injury repeatedly has demonstrated the reliability of using plasma phosphor-tau levels to help distinguish injury from normal, and severe injury from mild injury.

EEG-based Metrics After Severe Brain Injury

In this cohort study of 104 patients with disorders of consciousness, the authors demonstrated a strong correlation between EEG-based metrics and clinical diagnosis using quantitative behavioral scales, brain metabolism as measured by PET, and clinical outcomes at one year.

Mild Traumatic Brain Injury Induces Altered Sleep and Impaired Memory

Traumatic brain injury may induce a chronic state of altered sleep with impaired memory consolidation and mood disorders.

Serum and CSF Biomarkers of Brain Injury After Sports-related Concussion

ABSTRACT & COMMENTARY: So far none of the currently measured biomarkers has sufficient sensitivity or specificity to be clinically useful.

Linking Traumatic Brain Injury and Parkinson’s Disease: The Evidence Builds

A retrospective study based on an administrative database compared more than 50,000 admissions with traumatic brain injury (TBI) with more than 100,000 admissions for other traumatic injury, and found that TBI in individuals older than 55 years of age led to a 44% increased risk of developing Parkinson’s disease in the ensuing 5-7 years.

Does Traumatic Brain Injury Cause Sleep Disruption?

In a well-designed animal model of traumatic brain injury, a sleep disorder was induced that resembles, in many ways, what is observed in spontaneous human narcolepsy.