Clinical
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FAME Data Shows Durability of Fractional Flow Reserve Strategy at 5 Years
The 5-year results of the FAME study did not show any late catch up in major adverse cardiac events in the fractional flow reserve-guided group, supporting the long-term safety of the fractional flow reserve-guided approach to percutaneous coronary interventions.
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Management of Functional Mitral Regurgitation
In symptomatic patients with coronary artery disease, left ventricular ejection fraction < 30%, and significant mitral valve regurgitation, coronary bypass graft surgery (CABG) or CABG plus mitral valve repair should be considered.
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Remote Hemodynamic Monitoring Shows Long-term Benefit in Heart Failure Patients
Remote pulmonary artery pressure monitoring in New York Heart Association class III heart failure patients resulted in fewer subsequent hospitalizations and was well tolerated.
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Spironolactone for Resistant Hypertension
ABSTRACT & COMMENTARY: A study says spironolactone is superior to doxazosin and bisoprolol for lowering blood pressure.
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Recurrence Rate for Placental Abruption
A study from the Netherlands involving more than 1 million patients has shown that recurrence of placental abruption happens more frequently in those patients whose first abruption occurred at term and/or in their first pregnancy, as well as in those with a history of hypertension.
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Hormone Replacement Therapy Controversies: Have We Harmed Women?
The interpretation of hormone replacement therapy in postmenopausal women has varied dramatically before and after the publication of the Women’s Health Initiative study in 2002. New studies question the validity of the conclusions reached by the investigators.
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Molecular Diagnostics: A Step Forward in Breast Cancer Treatment?
Use of a gene-expression assay to predict prognosis may reduce the need for adjuvant chemotherapy in some women with early stage invasive breast cancer.
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New Data on Atraumatic Tenaculum Pain Scores
ABSTRACT & COMMENTARY: There was no difference in pain scores between the standard single-tooth tenaculum and the atraumatic vulsellum tenaculum.
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Clinical Briefs
In this section: no payoff to physical therapy after healed ankle fracture; bisphosphonates and bone recurrence; and manipulating the microbiome.
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No More Bacon? Carcinogenicity of Meat
A review of published research by the World Health Organization concludes that processed meats are probably carcinogenic.