Clinical
RSSArticles
-
Naloxone Nasal Spray (Narcan)
The FDA has approved naloxone in the form of a nasal spray as a life-saving medication to reverse the effects of an opioid overdose.
-
Nicotinamide Chemoprevention for Skin Cancer Is Impressive
In a Phase III, double-blind, randomized, placebo-controlled trial, oral nicotinamide was safe and effective in reducing the rates of new nonmelanoma skin cancers and actinic keratoses in high-risk patients.
-
Vitamin D Levels and Cognitive Function: Does It Make a Difference?
Similar to previous studies, vitamin D deficiency and insufficiency rates were not significantly different between those with normal cognitive status, mild cognitive impairment, or dementia. However, cognitive decline occurred at a significantly greater rate in individuals with low 25-hydroxyvitamin D levels in the areas of episodic memory and executive function.
-
Is it Normal Aging or Chronic Kidney Disease?
Current clinical guidelines for the diagnosis of chronic kidney disease resulted in more than half of adults > 70 years of age having chronic kidney disease. Should these guidelines change to require age calibration for diagnosis and classification of chronic kidney disease?
-
FDA Actions
In this section: the FDA approves a nasal spray to cease or reverse opioid overdose, recommends stronger warning labels on fluoroquinolones, and greenlights a once-daily, fixed-dose combination pill for treating HIV-1 infection.
-
Breakthrough in Hepatitis C Treatment?
New drug shows promise in recent trial.
-
AMA: Ban Direct-to-Consumer Ads
The American Medical Association is concerned the billions of dollars spent on drug and device ads is “driving demand for expensive treatments despite the clinical effectiveness of less costly alternatives” and is “fueling escalating drug prices.”
-
Sildenafil Improves Insulin Sensitivity
Chronic use of sildenafil (Revatio, Viagra) improves insulin sensitivity in prediabetics, according to a new study.
-
Group Calls for Generic Drug Use
The American College of Physicians recommends the use of generic medications when possible.
-
Expanding Safe Prescribing for Metformin
In an era of progressively more expensive interventions for type 2 diabetes, clinicians may wish to re-evaluate the boundaries of safe prescribing for metformin.