Clinical
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Small Vessel Disease Often Accompanies Large Vessel Intracranial Atherosclerosis
The SAMMPRIS trial investigated the consequences of medical vs endovascular therapy for the treatment of symptomatic intracranial atherosclerosis, and points out the high prevalence of coexisting small vessel disease with large vessel atherosclerosis.
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Loss of Consciousness at Onset of Aneurysmal SAH: Poor Prognosis
Loss of consciousness at onset of Aneurysmal subarachnoid hemorrhage is an indicator of early brain injury and predicts poor functional outcome or death at 12 months.
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Left Atrial Dysfunction Without Fibrillation Increases Stroke Risk
Lleft atrial abnormalities that do not necessarily result in atrial fibrillation, may also increase the risk of stroke and should be investigated and searched for in patients with ischemic stroke consistent with cardiogenic embolism.
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Vision Problems After Ischemic Stroke: Effects on Quality of Life
Visual impairments are common in stroke survivors and should prompt a careful ophthalmologic evaluation, since many of the problems are ocular and not neurological.
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Acetylcholine Receptor Antibody Testing in Ocular Myasthenia Gravis
More than two-thirds of patients with ocular myasthenia will have a positive antibody test, and a high level may predict progression to generalized disease.
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Simvastatin and Vitamin D for Migraine Prevention
In a randomized, double-blind, placebo-controlled trial of 57 adults with episodic migraine, simvastatin plus vitamin D was effective in the prevention of headache in adults with episodic migraine.
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Disability, Anxiety, and Depression with Medication-overuse Headache
A brief intervention that focuses on patient education can be effective in reducing headache frequency and medication dependency in patients with medication overuse headache.
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Clinical Features and Treatment Response in Patients with NMO Spectrum Disorders
In a retrospective analysis of 871 relapses in 185 patients with neuromyelitis optica or an neuromyelitis optica spectrum disorder, the authors reported that more than 80% of patients will have a partial or complete remission from their initial course of therapy.
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Kirtan Kriya Meditation on Stress and Alzheimer’s Disease
This review article shows that meditation, particularly Kirtan Kriya, can mitigate the negative biochemical effects of stress.
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Emergency Department Visits Related to Dietary Supplements
A 10-year chart review of 63 nationally representative emergency departments reveals 3667 cases of adverse events related to dietary supplement use; these are estimated to represent 23,005 emergency department visits yearly. Characteristics of the visits are described and categorized.