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Can Antibiotic Exposure Cause Some Mood Disorders?

Since gut flora alteration through antibiotic administration is a commonplace experience for most adults, might such exposures, by altering the intestinal microbiome, also be associated with mood disorders in humans?

Systemic Markers of Hidradenitis Suppurativa

Measurement of C-reactive protein, an inexpensive and readily available test, in hidradenitis patients may enhance assessment of disease severity.

ECG Review: Early Repolarization or Something More?

Clinical Briefs

In this section: potential good cardiovascular news; spironolactone best add-on for resistant hypertension; and questions about Vitamin D for primary care practice.

Mepolizumab Injection (Nucala)

Mepolizumab is indicated for add-on maintenance treatment of adult patients ≥ 12 years of age with severe asthma and with an eosinophilic phenotype.

Carotid Occlusion Rarely Develops from Asymptomatic Carotid Artery Stenosis

Recent study indicates that the risk of progression to carotid occlusion is well below the risk of carotid stenting or carotid endarterectomy.

Utility of Non-traditional Risk Factors in Patients Ineligible for Statin Therapy

Adding additional risk factors not in the pooled risk equation to low-risk subjects identified a sub-group with an observed event rate > 7.5% who may warrant statin therapy.

Effect of Modified Valsalva Maneuver for Emergency Treatment of Supraventricular Tachycardia

In patients presenting with supraventricular tachycardia, a modified Valsalva maneuver with leg elevation and supine positioning at the end of strain was demonstrated to be more effective than the standard Valsalva maneuver at restoring normal sinus rhythm.

HPV vaccine update: Get up to speed

Healthcare professionals need to be familiar with all of the indications for the human papillomavirus vaccine, make strong recommendations for receiving vaccine at ages 11 or 12, and be aware of systems that can improve practice vaccination rates.

Chlamydia, gonorrhea, and syphilis cases are up for first time since 2006

Reported cases of chlamydia, gonorrhea, and syphilis have increased for the first time since 2006, according to just-published data by the Centers for Disease Control and Prevention.