Cardiology
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Adjuvanted Zoster Vaccine: Persistent Protection
The adjuvanted recombinant zoster vaccine efficacy is high and persistent, with apparent plateauing at > 84% four to six years after vaccination.
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First-Line Therapy for Hypertension
When comparing angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (ARBs) to treat hypertension, researchers observed no difference in major cardiovascular events — but a better safety profile for ARBs.
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Carbohydrates and Insulin Resistance: Pondering Food Quality vs. Quantity
Researchers posit that solving the obesity epidemic is not as simple as eating less and moving more.
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Vitamin D and COVID-19
Low levels of vitamin D are associated with in-hospital mortality in patients with COVID-19, but causality is not yet known.
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Rapid Eye Movement Sleep Duration Is Predictive of Life Expectancy
Total sleep duration declines with older age, as does the fraction of sleep spent in rapid eye movement (REM) sleep. The decline in REM is associated with increasing mortality, but it is unclear if this is a cause or a marker of declining health and declining brain function.
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Cannabis Use and Associated Health Conditions in Primary Care: An EHR Review
This cross-sectional review of 185,565 patients’ medical records revealed documentation of medicinal cannabis use in 2% of the records. Within this subgroup, 44.5% had documentation of one or more health conditions potentially benefitting from treatment with cannabis, 54.4% had documentation of one or more health conditions potentially worsening with cannabis use, and 36.6% had both types of health conditions.
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Is There a Role for Intermediate-Dose Anticoagulation for Critically Ill COVID-19 Patients?
In a multicenter, randomized clinical trial of critically ill COVID-19 patients, intermediate-dose compared to standard-dose prophylactic anticoagulation did not result in significant differences in the rates of venous or arterial thrombosis, treatment with extracorporeal membrane oxygenation, or mortality within 30 days.
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Dexmedetomidine for Sedation in Patients Undergoing Mechanical Ventilation in the ICU
This special feature will focus on dexmedetomidine as a sedative for invasive mechanical ventilation in the ICU.
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USPSTF Recommends Against Using Aspirin as a Heart Attack Prevention Tool
Instead of protecting against various cardiovascular ailments, the drug might cause more harm than good in otherwise healthy older patients.
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Report: Still Not Enough Women Included in Cardiovascular Research
To augment the enrollment of women in cardiovascular trials, researchers must build awareness of cardiovascular risk factors and foster trust among women. Try increasing the percentage of women who lead clinical trials, modifying inclusion and exclusion criteria, and advertising the risks and benefits of participation to the general population.