Cardiology
RSSArticles
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Long-Term Outcomes of Peripartum Cardiomyopathy
A large, prospective, observational study from Israel of peripartum cardiomyopathy has shown that, in general, outcomes are favorable, with high rates of left ventricular function recovery that remain stable and with no mortality but also that show high rates of cardiovascular comorbidities during long-term follow-up.
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Early vs. Late Catheter Ablation for Atrial Fibrillation in Older Patients
An observational study from China in older patients with persistent atrial fibrillation (AF) has shown that an earlier diagnosis to catheter ablation time of ≤ 12 months compared to > 12 months is associated with lower rates of AF recurrence and adverse cardiovascular outcomes.
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Ablation vs. Drugs for Ventricular Tachycardia
A sub-analysis of the VANISH2 trial, which compared catheter ablation (CA) to antiarrhythmic drug therapy for the suppression of ventricular tachycardia (VT) in patients with ischemic cardiomyopathy has shown that in the sotalol therapy group, those randomized to CA less frequently experienced the VT-based composite endpoint. Conversely, in the amiodarone group, the primary endpoint was similar in the CA- and drug therapy-randomized patients, but amiodarone produced more adverse events.
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Improved Major Arrhythmic Event Prediction in Non-Ischemic Cardiomyopathy
An international multicenter registry study of patients with non-ischemic cardiomyopathy without a history of major arrhythmic adverse cardiac events (MAACE) that compared a new cardiac magnetic resonance imaging score for predicting MAACE and consequently determining the need for a primary prevention implantable cardioverter defibrillator has found that this new score is superior to the standard left ventricular ejection fraction criterion.
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Novel Drug-Coated Balloon Compares Favorably to DES in De Novo Disease and ISR
In two related largest-to-date clinical trials, a sirolimus-eluting balloon was noninferior to current-generation drug-eluting stents (DES) in both de novo lesions and in-stent restenosis (ISR).
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The History Matters!
How would you interpret today’s 12-lead electrocardiogram and long lead V1 rhythm strip if the history was that of an older adult with known coronary disease? Would your interpretation change if, instead, the patient was a younger adult with a known history of severe congenital heart disease, having been operated on a number of times as a child?
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Paltusotine (Palsonify) Tablets
The U.S. Food and Drug Administration has approved paltusotine, the second oral (after octreotide), but first once-daily formulation for the treatment of acromegaly in adults.
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Psychiatric Medications and Long QT Syndrome: A Safe Combination?
A retrospective study of patients with electrocardiogram long QT interval syndrome and psychiatric disease suggests that with proper pharmacologic treatment and counseling, the patients can be treated safely with psychiatric drugs known to increase the QT interval.
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Efficacy of Adding Aspirin to OACs for CAD Patients
A randomized, placebo-controlled trial of adding aspirin to oral anticoagulant therapy in patients with chronic coronary artery disease at high risk of atherothrombotic complications and major bleeding was stopped early because aspirin increased the risk of all-cause mortality. In addition, aspirin was associated with an increase in atherothrombotic complications and major bleeding.
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Psychiatric Medications and Long QT Syndrome: A Safe Combination?
A retrospective study of patients with electrocardiogram long QT interval syndrome and psychiatric disease suggests that with proper pharmacologic treatment and counseling, the patients can be treated safely with psychiatric drugs known to increase the QT interval.