Cardiology
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Sarecycline Tablets (Seysara)
Sarecycline is indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne in patients 9 years of age and older.
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Is Sanitizer Better Than Soap?
In day care settings, the implementation of hand hygiene programs reduced respiratory illness, absenteeism, and antibiotic use in children 0-3 years of age. Using hand sanitizer was more effective than washing with soap and water.
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Trends in Supplemental Vitamin D Intake
Researchers investigated the trends in daily supplemental vitamin D intake of ≥ 1,000 IU and ≥ 4,000 IU and found increasing use of vitamin D supplementation.
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Exercise and the Aging Immune System
The authors of this literature review detailed changes in immune system function that occur with age, as well as the immunological effects of acute and chronic exercise.
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The Effect of Vitamin D Supplementation on Fractures, Falls, and Bone Mineral Density
The authors of this systemic review, random-effect meta-analysis, and trial sequence analysis suggested that vitamin D supplementation does not have clinically significant effects on bone mineral density or the prevention of fractures or falls.
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Weight Loss Maintenance — Is Low-Carb the Key? An Investigation Into the Metabolic Effect of Diet
Researchers found that among adults seeking to maintain weight loss, consumption of a low-carbohydrate diet led to the highest total energy expenditure.
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Lettuce for Sleep? Maybe, but Not in Salad Form
The authors of this single-blind randomized study found that 1,000 mg of culinary lettuce seed nightly for two weeks can improve sleep in pregnant women with insomnia.
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Prucalopride Tablets (Motegrity)
Prucalopride is indicated for the treatment of chronic idiopathic constipation in adults.
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Should Acute Appendicitis Be Managed Without Appendectomy?
A retrospective cohort study that used national insurance claims data revealed patients with acute appendicitis who were treated nonsurgically experienced higher rates of complications and higher overall care costs.
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Alcohol Use: No Safe Level
A systematic analysis of data from the Global Burden of Disease Study 2016 on alcohol-linked disorders and patterns of alcohol use over 25 years worldwide found there is no safe level of alcohol consumption.