Cardiology
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Management of Spontaneous Coronary Artery Dissection
In the largest study to date about patients with spontaneous coronary artery dissection who underwent follow-up angiography, 95% of those who underwent repeat cath more than 30 days later showed spontaneous angiographic healing.
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Impact of Atrial Fibrillation on Survival in Patients With Severe Mitral Regurgitation
A large observational study of patients with severe mitral valve regurgitation due to flail leaflets revealed that atrial fibrillation at entry was associated with excess mortality.
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Who Needs a TEE Prior to Atrial Fibrillation Cardioversion?
A study of patients with atrial fibrillation or flutter undergoing transesophageal echocardiography showed a left atrial appendage thrombus in 8% overall and 4% in those appropriately anticoagulated.
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Medication First? Ablation First? Either Way, Make Weight Loss a Priority
Weight loss management and aggressive risk factor modification associated with slowing or even reversal of atrial fibrillation progression.
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Withdrawal of Medical Therapy Associated With Relapse in Recovered Dilated Cardiomyopathy
In patients with dilated cardiomyopathy and recovered ejection fraction, discontinuation of heart failure medical therapies was associated with a 44% risk of relapse within six months.
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Are the Changes Acute?
Imagine the ECG in the figure was obtained from a previously healthy, middle-aged man who presented to an ambulatory clinic for “indigestion.” How might one interpret the ECG?
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Caplacizumab-yhdp for Injection (Cablivi)
Caplacizumab-yhdp is indicated for the treatment of acquired thrombotic thrombocytopenic purpura in combination with plasma exchange and immunosuppressive therapy.
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Homeless Population Requires Hepatitis A Vaccination
A multistate outbreak of hepatitis A virus (HAV) infection in the homeless and/or drug-using population has prompted the United States Advisory Committee on Immunization Practices to add “homelessness” as an indication for HAV vaccination. This is in addition to existing indications for HAV vaccination of men who have sex with men and illicit drug users (with the exception of marijuana use).
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Combination Drug Therapy for Hypertension
A large regional database study from Italy revealed that initial combination therapy for newly diagnosed hypertension results in fewer major adverse cardiovascular events at one year compared to monotherapy.
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Clinical Outcomes After Oral Anticoagulant-Associated Intracerebral Hematoma
In this meta-analysis of multiple observational studies, clinical outcomes after oral anticoagulant-associated intracerebral hematoma were similar for those associated with vitamin K antagonists or the new class of direct oral anticoagulants.