Browse OB/GYN Clinical Alert Articles by Topic

Tenaculum Placement Techniques and Effect on Pain

In this randomized controlled trial, there was no difference in pain score with tenaculum placement between the slow method of application and coughing with application (median pain score 44 vs. 32, P = 0.16).

What Are the Roles of the Combined Oral Contraceptive Pill and Metformin in the Management of Polycystic Ovary Syndrome?

This systematic review documents the effectiveness of combined oral contraceptive pills in treating hyperandrogenism and irregular menses, and of metformin in addressing the metabolic disturbances in women with polycystic ovary syndrome.

The Affordable Care Act: Progress in Reducing the Rate of Unintended Pregnancy

Data from the latest release of the National Survey of Family Growth supports that the contraception coverage mandate of the Affordable Care Act has resulted in a decrease in the incidence of unintended pregnancy, particularly among women with government coverage.

PARP Inhibitors: An Adjunct to Initial Standard Treatment for Advanced Ovarian Cancer Patients

The PRIMA study is a randomized, double-blind, multi-institutional, international phase 3 trial testing the PARP inhibitor niraparib against placebo after first-line standard treatment with platinum-based chemotherapy for newly diagnosed ovarian cancer.

Influenza and Pertussis Vaccines for Pregnant Women: Are We Doing Enough to Encourage Vaccination?

In this cross-sectional analysis, pregnant women disproportionately accounted for 24-34% of influenza-associated hospitalizations among women aged 15 to 44 years, and infants younger than 2 months of age comprised the highest proportion of pertussis deaths. The reasons why pregnant women did not elect recommended immunizations included not believing they were effective, not knowing they should receive Tdap every pregnancy, and being concerned that the vaccines would harm the fetus.

News From the WHI: Soft Drink Consumption and Bone Health

Participants from the Women’s Health Initiative study who reported consumption of more than two soft drinks per day showed a higher incidence of hip fracture compared to those consuming no soft drinks.

To Sling or Not to Sling at the Time of Pelvic Organ Prolapse Repair?

Knowing the best way to counsel patients regarding the risks, benefits, and alternatives of performing an incontinence procedure at the time of reconstructive pelvic surgery for pelvic organ prolapse (POP) can be challenging.

Gabapentin for Pain Reduction During First-Trimester Uterine Aspiration

In this randomized, double-blind, placebo-controlled trial, 600 mg of oral gabapentin administered one to two hours pre-procedure did not reduce pain during or after first-trimester surgical abortion.

Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?

An individual-participant meta-analysis of prospective studies found menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.

Maternal Sleep Position and Pregnancy Outcomes

Questions regarding sleep position safety are often posed for any OB/GYN or midwife practicing obstetrics.