Browse OB/GYN Clinical Alert Articles by Topic

Is RhoGAM Needed for Rh-Negative Women Experiencing First-Trimester Pregnancy Loss or Induced Abortion?

In this prospective cohort pilot study, the authors validated a flow cytometry protocol for detecting fetal red blood cells and determined that fetal red blood cell exposure in first-trimester uterine aspiration was well below the calculated threshold for maternal Rh sensitization.

Restricting Access to Abortion Increases Complications

Restrictive abortion laws increase the chance that a woman will self-manage her abortion, a practice associated with an increased risk of complications.

Should Metronidazole Be Added Routinely to Treatment Regimens for PID?

In this randomized, double-blind, controlled trial, routine treatment with metronidazole compared to placebo in addition to doxycycline and ceftriaxone reduced the presence of endometrial anaerobes, Mycoplasma genitalium, and pelvic tenderness at 30 days post-treatment. However, clinical improvement at three days post-treatment was no different between the two groups.

COVID-19 and Pregnancy: What Obstetricians Need to Know

While data remain limited on this particular coronavirus, extrapolation from other viruses (severe acute respiratory syndrome and Middle East respiratory syndrome), and best clinical observations and expert recommendations have led to current guidelines in care.

Diet Modification in Older Women with Fecal Incontinence

Older women with fecal incontinence manage their symptoms with dietary modification.

The Global COVID-19 Pandemic Was Predicted and Ignored

The human population explosion, international travel and migration, urbanization, and environmental exploitation set the stage for pandemics, and the trend likely will continue and intensify.

Young Cancer Survivors at Increased Risk of Subsequent Endocrine Disease

A large Danish-based population cohort study documents that survivors of cancers arising in adolescence and young adulthood are at increased risk of subsequently developing a variety of endocrine disorders.

Impact of Weight Loss on Lower Urinary Symptoms and Urinary Incontinence in Overweight and Obese Women

Weight loss interventions are associated with improvements in urinary incontinence in overweight and obese women at 1 to 2.9 years.

Does Talcum Powder Cause Ovarian Cancer?

In this analysis of four large cohort studies, genital talcum powder use was not found to have any association with ovarian cancer.

17P to Prevent Recurrent PTB in Singleton Gestations: The PROLONG Study

In this large, double-blind, placebo-controlled, international trial, pregnant women at risk for preterm birth (PTB) between 16-36 weeks gestational age were randomized to an intramuscular weekly injection of either 17-hydroxyprogesterone caproate (17P) or placebo. There was no difference in rates of PTB or neonatal morbidity between these two groups. In comparison to the Meis trial published in 2003, the findings of the PROLONG trial question the use of intramuscular 17P injection as the cornerstone of PTB prevention.