Browse Neurology Articles by Topic

Ibalizumab-uiyk Injection (Trogarzo)

Ibalizumab-uiyk, in combination with other antiretrovirals, is indicated for the treatment of HIV-1 in heavily treatment-experienced adults with multidrug-resistant HIV infections failing their current regimens.

After Myocardial Infarction, Increased Risk for Ischemic Stroke Persists for 12 Weeks

This study establishes that the elevated short-term risk of stroke extends beyond 30 days and remains elevated for up to 12 weeks following acute myocardial infarction.

Stroke Risk in Atrial Fibrillation: A Moving Target?

An investigation of patients in a national database with atrial fibrillation, no comorbidities, and not on aspirin or anticoagulants showed that the clinical features that make up the CHA₂DS₂-VASc score change over time and can increase a patient’s risk for stroke, which could affect therapy decisions. Thus, the CHA₂DS₂-VASc score should be reassessed periodically and appropriate therapeutic actions taken promptly.

Elderly May Not Benefit From Statins for Primary Prevention

In an examination of the data from the much-publicized Systolic Blood Pressure Intervention Trial (SPRINT), the author found no benefit of statin therapy for primary prevention of cardiovascular events or all-cause mortality.

A Possible New Treatment for HTLV-1-associated Myelopathy

Mogamulizumab reduces central nervous system inflammation and improves spasticity in patients with HTLV-1-associated myelopathy.

Parsonage-Turner Syndrome: Where’s the Lesion?

SYNOPSIS: This careful analysis of MRI imaging of the brachial plexus in patients with well-defined Parsonage-Turner Syndrome showed that the lesions are in peripheral branches of the brachial plexus and not in the roots or cords.

Lessons Learned From a Failed Anti-amyloid Trial for Alzheimer’s Disease

Despite the disappointing results in EXPEDITION 3, modifications of clinical trials for Alzheimer’s disease (AD) should be undertaken and trials targeting preclinical or early AD should continue with anti-amyloid agents.

Postpartum Headache May Be a Symptom of a Serious Problem

Consultation for acute postpartum headache resulted in the diagnosis of a secondary cause of headache in almost three out of four women, with almost half of the secondary headaches due to a hypertensive disorder of pregnancy or to cerebrovascular disease.

Coprescription of Triptans and SSRI-type Medications and the Serotonin Syndrome

A recent study provided reassurance that the use of triptan antimigraine medications with selective serotonin reuptake inhibitor and selective norepinephrine reuptake inhibitor antidepressants is safe.

Autoimmune Encephalitis: Not Rare and Increasing

Detection of autoimmune encephalitis is increasing over time. According to the results from this population-based study, its prevalence and incidence are comparable to infectious encephalitis.