Browse Neurology Alert Articles by Topic

Prehospital and Emergency Care

These articles are based on the editor's personal interactions as a participant at the International Stroke Conference in Houston, Feb. 22-24, 2017. All interpretations and opinions are exclusively those of the editor.

Prevention and Risk Factor Reduction

These articles are based on the editor's personal interactions as a participant at the International Stroke Conference in Houston, Feb. 22-24, 2017. All interpretations and opinions are exclusively those of the editor.

First-ever Study of Genome Sequencing in the Common Forms of Epilepsy

In the first study with genome sequencing in the common forms of epilepsy, ultra-rare genetic mutations of known epilepsy genes were over-represented in the epilepsy population, compared to controls.

EEG Reactivity Testing in Comatose Patients After Severe Brain Injury

Studies assessing EEG reactivity in comatose patients after severe brain injuries are highly variable and almost never provide replicable definitions for presence or absence of EEG reactivity, even though it is used increasingly as a prognostic measure.

Guillain-Barré Syndrome and Hepatitis E

Hepatitis E is the most common form of viral hepatitis worldwide and often is asymptomatic. But it is commonly associated with Guillain-Barré syndrome and Guillain-Barré variants.

Differences in Disease Duration in LBD May Be Related to Pathologic Burden

This observational study of 807 autopsy-confirmed cases of Lewy body disease used Braak neurofibrillary tangle staging, frequency of neuritic plaques, and Lewy body staging to demonstrate that those individuals who had diffuse LBD had a shorter disease duration than those with transitional LBD localized to the limbic region.

Ocrelizumab for Multiple Sclerosis

A Phase III trial of ocrelizumab in primary-progressive multiple sclerosis and two Phase III trials of ocrelizumab in relapsing-remitting multiple sclerosis have demonstrated efficacy with treatment.

New Tools for the Diagnosis of CJD

Cerebrospinal fluid analysis using second-generation, real-time, quaking-induced conversion has a high sensitivity and specificity for the diagnosis of Creutzfeldt-Jakob disease.

Migraine: Differences Between Males and Females

Hormonal and genetic differences factor into a greater prevalence and disability burden of migraine in teenaged girls and women; however, migraine is underdiagnosed and inadequately treated in boys and men.

Ambulatory Autonomic Testing in Multiple System Atrophy and Parkinson’s Disease

A comparison of ambulatory blood pressure monitoring with tilt-table testing in 23 patients with multiple system atrophy, 18 with Parkinson’s disease and autonomic dysfunction, and 33 with Parkinson’s disease alone demonstrated 82% sensitivity and 100% specificity in detecting orthostatic hypotension. This suggests ambulatory monitoring provides valuable information on these patients’ function.