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A Population-Based View into the Incidence and Etiology of Papilledema

In a population-based study in Olmstead County, MN, during the period 1990 to 2014, the incidence of papilledema was 2.5/100,000 persons per year, and most patients were diagnosed with idiopathic intracranial hypertension.

Expansion and Versatility of Telemedicine During the COVID-19 Pandemic

Telemedicine has rapidly transformed healthcare delivery during the COVID-19 pandemic, but innovative reimbursement models and updated privacy regulations are needed to ensure widespread implementation of high-quality digital care.

Two Possible Mechanisms of Disease in COVID-19

COVID-19 infection may be associated with an increased risk of blood clotting and related thrombotic events, but there are insufficient data to support indiscriminately discontinuing medications that play a critical role in the management of chronic cardiovascular disease.

Guillain-Barré, Miller Fisher Syndrome, and Associated Disorders in Patients with COVID-19

As the COVID-19 pandemic spreads around the world, investigators in multiple countries are reporting patients with myriad cranial and peripheral nerve disorders that have some, but not all, features of Guillain-Barré syndrome.

The Effect of Coronaviruses on the Central Nervous System

Known coronaviruses can enter the central nervous system by different pathophysiologic mechanisms. Neurological presentations linked to the novel SARS-CoV-2 include encephalopathy, encephalitis, cranial neuropathies, Guillain-Barré syndrome and other neuropathies, and ischemic and hemorrhagic strokes.

Neurologic Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China

Neurological symptoms and impairments have been found in one-third of hospitalized patients with COVID-19 from countries that have reported these observations so far. This is a rapidly evolving consequence of SARS-CoV-2 infection.

Cognitive Symptoms in Genetic Forms of Parkinson’s Disease May Help in Distinguishing the Various Types

This paper illustrates that, of the confirmed genetic forms of Parkinson’s disease, there are common cognitive and psychiatric features, thus adding to our knowledge of the clinical phenotype of these genetic forms.

Zilucoplan for Myasthenia Gravis

Zilucoplan, a macrocyclic peptide that binds complement component C5, showed promise as an effective agent for treatment of generalized myasthenia gravis in a Phase II trial.

Special Report from the 2020 International Stroke Conference, Los Angeles

These reviews of studies presented at the 2020 International Stroke Conference were written by Neurology Alert's editor after personal attendance at the presentations, followed by review of the simultaneous publications in Stroke. All comments and opinions are solely those of the editor.

Vegetarians and Stroke

A prospective cohort study in the United Kingdom demonstrated that vegetarians have a 22% lower incidence of ischemic heart disease, but a 20% increased incidence of total stroke, mostly related to hemorrhagic stroke, when compared to meat eaters. No difference in ischemic stroke or acute myocardial infarction was found.