Internal Medicine
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Is Long-Term Antidepressant Use Hurting Patients?
Long-term antidepressant use could lead to elevated risks of coronary heart disease, along with higher cardiovascular disease mortality and all-cause mortality rates.
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Deucravacitinib Tablets (Sotyktu)
Deucravacitinib can be prescribed to adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
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Increasing Incidence of Stage IV Cervical Cancer
The incidence of stage IV cervical cancer in the United States between 2001 and 2018 increased. Rates were highest among Black women, but the annual rate of increase was highest among white women in the South age 40-44 years.
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Vitamin D3, Omega-3 Supplements for Older Adults to Lower Frailty Risk
Data from a large, randomized trial that included 25,871 adults age 50 years or older indicated 2,000 daily units of vitamin D3 and 1 g daily of omega-3 fatty acid supplementation did not affect frailty.
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Importance of Medication Adherence in Ischemic Heart Disease
The results of a subanalysis of the ISCHEMIA trial indicated about one-quarter of patients in both conservative and invasive strategy groups were nonadherent to recommended medical therapy at baseline. Nonadherence was associated with worse health status in both groups at baseline and after one year.
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Evidence of Clinical Efficacy of Bebtelovimab in COVID-19
In a retrospective study, bebtelovimab demonstrated efficacy similar to Paxlovid in high-risk outpatients with recent onset of COVID-19 who reported mild to moderate symptoms.
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Spironolactone May Help Treat Chronic Alcoholism
Both animal and human studies suggest spironolactone might be a new agent for helping patients with alcohol use disorder cut their intake.
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MicroRNA Could Help Oncologists Craft Better Treatment Plans for Breast Cancer Patients
Researchers have been searching for biomarkers that are good predictors of cancer recurrence and mortality.
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Sodium Phenylbutyrate and Taurursodiol for Oral Suspension (Relyvrio)
Relyvrio can be prescribed to treat amyotrophic lateral sclerosis in adults.
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The Dental Procedure-Infective Endocarditis Link Controversy Continues
Infective endocarditis was more common with dental surgery or tooth extractions in the preceding four weeks in high-risk patients. Researchers abrogated this risk with antibiotic prophylaxis before the procedure.