Internal Medicine
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Patients with Chronic Pain and Opioid Misuse: What Treatment Works?
Among primary care patients diagnosed with comorbid chronic pain and opioid misuse, researchers found a specially designed, mindfulness-based group therapy showed superiority to generic supportive group therapy in reducing opioid use and controlling symptoms of chronic pain.
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The Clue in Lead II
How should one interpret the ECG in the figure? The figure was obtained from a 40-year-old man who was hemodynamically stable at the time this tracing was recorded. The key clue is in lead II.
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Ruxolitinib Cream (Opzelura)
Ruxolitinib cream can be prescribed to treat nonsegmental (bilateral) vitiligo in adult and pediatric patients age 12 years and older.
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Periodontal Disease as an Independent Risk Factor for Cardiovascular Disease
Researchers used data from the 2013 to 2014 period of the National Health and Nutrition Examination Survey to study possible connections between poor oral health and the likelihood of developing cardiovascular disease.
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Is Illicit Substances Use Associated with Atrial Fibrillation?
An observational study of a huge cohort of patients admitted to California hospitals showed patients who used cocaine, methamphetamine, opiates, and cannabis were at a higher risk of developing atrial fibrillation vs. those with similar risk factors who did not use the substances.
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The Right Dose at the Right Time: Improving Hypertension Outcomes
An online study of evening vs. morning administration of patients’ usual antihypertensive medications, with a median five-year follow-up, revealed there is no difference in major cardiovascular outcomes between the two periods.
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Is Long-Term Antidepressant Use Hurting Patients?
Long-term antidepressant use could lead to elevated risks of coronary heart disease, along with higher cardiovascular disease mortality and all-cause mortality rates.
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Deucravacitinib Tablets (Sotyktu)
Deucravacitinib can be prescribed to adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
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Increasing Incidence of Stage IV Cervical Cancer
The incidence of stage IV cervical cancer in the United States between 2001 and 2018 increased. Rates were highest among Black women, but the annual rate of increase was highest among white women in the South age 40-44 years.
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Vitamin D3, Omega-3 Supplements for Older Adults to Lower Frailty Risk
Data from a large, randomized trial that included 25,871 adults age 50 years or older indicated 2,000 daily units of vitamin D3 and 1 g daily of omega-3 fatty acid supplementation did not affect frailty.