Browse Internal Medicine Articles by Topic

Expert Panel Debunks Common Sleep-Related Myths

Authors identified and deconstructed 10 misconceptions parents hold about teenage nocturnal patterns.

Top Heart Medication Could Help Alcohol Use Disorder Patients

Spironolactone is known to block mineralocorticoid receptors, an action believed to reduce alcohol cravings.

Irregular Sleep Could Cause More Inflammation

Those who slept few hours per night exhibited troubling signs of improper immune system function in a small study.

CDC: U.S. Adult Obesity Rate Up Sharply

At least 35% of adults are obese in 19 states and two territories.

CDC: Most Pregnancy-Related Deaths Are Preventable

Recent data indicate mental health conditions, excessive bleeding are the leading causes of pregnancy-related deaths in the United States.

Fraud Allegations Involving Alzheimer’s Disease Study Raise Concerns

In a paper published in 2006, the authors provided evidence indicating accumulation of a specific form of beta-amyloid protein was a cause of Alzheimer’s disease. However, recent accusations suggest images allegedly were altered, raising doubts about the initial conclusions. Regardless of what happened, this case has jumpstarted a conversation about instituting more preventive measures, conducting faster investigations into fraud allegations, and levying more severe consequences for researchers found guilty of misconduct.

Betibeglogene Autotemcel Suspension (Zynteglo)

The FDA has approved the first cell-based gene therapy to treat adult and pediatric patients with beta-thalassemia who require regular blood transfusions.

Remaining Questions in Syphilis Treatment

Eight leading experts on sexually transmitted diseases convened to discuss key questions in the management of syphilis in adults with and without HIV infection based on a systematic review of the literature. More than 3,000 articles were screened, and the discussion focused on 95 relevant publications and three main topics.

Appropriate Management of Thoracic Aortic Aneurysms

Among patients with arch and descending thoracic aorta aneurysms followed over a mean of 20 months, aneurysm-related mortality was predicted by the size and growth rate of the aneurysms, along with age and sex.

Predicting the Tolerability of Sacubitril/Valsartan in Advanced Heart Failure

An analysis of the sacubitril/valsartan run-in period for chronic, advanced heart failure patients showed 18% could not tolerate the lowest dose, usually because of hypotension or renal dysfunction. Investigators identified six predictors of non-tolerance, which may help clinicians choose the best candidates.