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Double BBB, or Complete AV Block?

The ECG in the figure is from a woman who complained she had been experiencing chest pain for several days. What is the rhythm? Is there complete AV block?

Zavegepant Nasal Spray (Zavzpret)

Zavegepant can be prescribed to treat migraine, with or without aura, in adults.

Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition

Researchers followed participants for three years and determined daily cocoa supplement use was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.

Influence of Vitamin Intake on Migraine Prevalence

Among participants experiencing severe headaches or migraine, those with severe headaches also reported a lower intake of thiamine and riboflavin, based on 24-hour recall of food intake.

Insulin Resistance at the Blood-Brain Barrier in Alzheimer’s Disease

Alterations in cerebrovascular insulin receptor isoform levels were associated with Alzheimer’s disease pathology and caused deficits in insulin signaling at the level of the blood-brain barrier.

Bone Density as a Dementia Risk Indicator

Researchers found some associations between bone density loss and a higher risk of developing dementia.

Sparsentan Tablets (Filspari)

Sparsentan can be prescribed to alleviate proteinuria in adults with primary immunoglobulin A nephropathy who are at risk of rapid disease progression — generally, a urine protein-to-creatinine ratio 1.5 mg/g or higher.

Long-Term Maintenance Therapy After Percutaneous Coronary Intervention

An extended six-year follow-up of the HOST-EXAM study revealed the consistent benefit of the primary endpoint of fewer major cardiovascular events and less bleeding with clopidogrel vs. low-dose aspirin monotherapy in post-percutaneous coronary intervention patients who were on dual antiplatelet therapy for one year.

Does COVID Vaccination Prevent Car Crashes?

In a large study, lack of COVID vaccination was associated with more incidents of car crash injuries.

Self-Treatment of Recurrent Benign Paroxysmal Positional Vertigo

Using a cell phone-based app, self-treatment of recurrent benign positional paroxysmal vertigo was feasible and effective in most patients.