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Understanding of etiologies, management, and outcomes of febrile neutropenia has improved in recent years, and it is now possible to identify patients at high risk for morbidity and mortality using demographic, historical, and laboratory indicators.
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The FDA has approved the combination of isosorbide dinitrate and hydralazine for the treatment of heart failure in the black (African decent) population.
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Recent guidance from the United States Preventive Services Task Force has affirmed the evidence-based value of screening male current/ex-smokers older than age 65 for abdominal aortic aneurysm.
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A review of 79 clinical trials involving diet plus medications for treating obesity with BMI > 27 found modest weight loss at 1 year with sibutramine, orlistat, phentermine, bupropion, and topiramate when compared to placebo pills, and probably also for diethylpropion and fluoxetine.
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The 12-lead ECG in the Figure was obtained from a 75-year-old woman who presented with shortness of breath but no chest pain. There is complete RBBB (right bundle branch block). What else do you see? In view of this clinical presentation, what should you be concerned about?
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A new study from England defines acute lower respiratory tract infection as an uncomplicated acute illness, with cough as the primary symptom and at least one symptom or sign localized to the lower respiratory tract including sputum, chest pain, dyspnea, or wheeze.
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By Barbara A. Phillips, MD, MSPH
Professor of Medicine, University of Kentucky; Director, Sleep Disorders Center, Samaritan Hospital, Lexington, KY Dr. Phillips serves on the speakers bureau of Cephalon, Boehringer Ingelheim, Merck, ResMed, and GlaxoSmithKline and is a consultant for Boehringer Ingelheim, Wyeth-Ayerst, and ResMed.
Synopsis: There was no overall effect of 100 mg aspirin every other day on total cancer among nearly 40,000 women randomized to aspirin or placebo and followed for an average of 10 years.
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Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment
Foot Small Muscle Atrophy Before the Detection of Clinical Neuropathy
Statins and the Risk of Colorectal Cancer
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By Harold L. Karpman, MD
Clinical Professor of Medicine, UCLA School of Medicine Dr. Karpman reports no financial relationship to this field of study.
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By Norm Latov, MD
Professor of Neurology and Neuroscience and Director of the Peripheral Neuropathy Center at Weill Medical College at Cornell University. Dr. Latov is a consultant for Quest Diagnostics and Talecris Inc., is a stockholder of Therapath LLC, and has royalties in Athena Diagnostics.
Synopsis: The availability of sensitive and reproducible measures of autonomic function has improved physicians ability to diagnose these disorders.
