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Inclisiran Injection (Leqvio)

Inclisiran can be prescribed as an adjunct to diet and maximally tolerated statin therapy for adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who required additional low-density lipoprotein cholesterol lowering.

Adverse Effects of Electronic Cigarettes on the Disease-Naïve Oral Microbiome

A robust metagenomic comparison study of the effects of electronic cigarettes on oral microbiomes suggested that the unique aerosol component of electronic cigarettes poses increased risk to development of oral cavity disease.

Plant-Based Diets and Menopausal Hot Flashes

Women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% vs. 49% in the control group over 12 weeks of observation.

Infections Before Age 20 Years Increase the Risk of Multiple Sclerosis

Researchers found patients diagnosed with infection in adolescence were at higher risk for multiple sclerosis, even after exclusion of infectious mononucleosis, pneumonia, and central nervous system infection.

New Dietary Guidance to Improve Cardiovascular Health: Meeting People Where They Are

The American Heart Association emphasizes the importance of an overall lifetime heart-healthy diet and the vital role of nutrition early in life.

List of Possible Cancer-Causing Agents Grows Longer

Six water disinfection byproducts, plus a flame retardant and a bacterial infection, now considered potential human carcinogens.

ED Is Focus of Reduction in Sepsis-Related Mortality

Using a sepsis alert, combined with nursing protocols and physician order set usage, can improve core measure compliance and related mortality rates.

Post-Exercise Premature Ventricular Contraction, or Aberrancy?

The ECG in the figure is a post-exercise tracing. There are four wider and slightly early occurring beats in the long lead rhythm strips. Are these beats premature ventricular contractions or premature atrial contractions conducted with aberration?

Nirmatrelvir and Ritonavir Tablets (Paxlovid)

The FDA has issued an emergency use authorization for the first oral regimen for the treatment of COVID-19.

Incidence, Prevalence, and Long-Term Consequences of Small Fiber Neuropathy

Small fiber neuropathy (SFN) associated with diabetes and other causes is more likely to progress to large-fiber polyneuropathy, deteriorate faster, and cause worse disability vs. slow progression with idiopathic SFN.