Infectious Disease
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When More Is Not Better: Treatment of Prosthetic Valve Endocarditis Due to Staphylococci
Clear evidence of benefit from adjunctive administration a β-lactam and/or a glycopeptide in the treatment of prosthetic valve endocarditis due to staphylococci is lacking. Current guidelines need to be reassessed.
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Resistance of SARS-CoV-2 Variants to Monoclonal Antibodies
Prevalent SARS-CoV-2 variants are increasingly resistant to therapeutic and prophylactic monoclonal antibodies but remain susceptible to Paxlovid, remdesivir, and molnupiravir.
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Salmonella Gastroenteritis — The Risk of a Rapid, Accurate Diagnosis
Availability of molecular testing panel results that were positive for Salmonella in children led to increased hospital admissions, increased subsequent microbiologic testing, and increased antibiotic use — all without benefit to patients.
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Statin Use with Daptomycin: Do We Finally Have a Definitive Answer?
A meta-analysis on published literature and a disproportionality analysis using Food and Drug Administration data found that statin use was associated with the occurrence of daptomycin-induced musculoskeletal adverse events. In most cases, statin use should be discontinued while patients are on daptomycin.
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Ethical Justification for Research on Dangerous Pathogens
Recent inflammatory headlines suggested researchers had created a more dangerous version of COVID. However, those researchers said the headlines were misleading. Nevertheless, it spotlighted the ethical concerns involving research on pathogens.
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It’s Not All About the Cough
Be careful about relying on clinical queries that focus on the presence of cough for two or more weeks, which could lead to delays in the diagnosis of nearly half of pulmonary tuberculosis cases.
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WHO Lobbies for Updated Tuberculosis Vaccines
International organization says these investments could drive economic growth, improve health equity and antimicrobial stewardship, and lower mortality rates.
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Congress Issues Special Report on COVID-19 Pandemic
A select subcommittee exhaustively detailed what went wrong and offered suggestions on how to prevent future disasters.
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Global Health Officials Announce Updated Name for Monkeypox
The traditional name will be phased out in favor of “mpox.”
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Infectious Disease Alert Updates
Animal Reservoirs for Human Infection; Novel Rat-Derived HEV Infection in Humans; Household Contamination with Monkeypox