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IPs Held the Line When AIDS Epidemic Hit U.S.

Currently president of the Association for Professionals in Infection Control and Epidemiology, Karen Hoffmann was a new IP at Detroit Medical Center 38 years ago. She recalls the day in 1981 when the Centers for Disease Control and Prevention released a report on the first cases of what eventually would be called AIDS. Hospital Infection Control & Prevention talked to Hoffmann about the IP experience during the epidemic in the following interview.

A Bold Strategy to End the AIDS Epidemic in the U.S.

While taking an overall national approach, the plan — part of a collaboration between the Centers for Disease Control and Prevention and other federal agencies — would target specific geographic areas and at-risk populations. The goals are a 75% reduction in infections in the next five years and a 90% reduction in 10 years.

Brexanolone Injection (Zulresso)

Brexanolone is indicated for the treatment of postpartum depression.

Update on Treatments for Vulvovaginal Atrophy

As with many clinical conditions, the spectrum of genitourinary syndrome of menopause requires the clinician to consider the effect on the patient’s quality of life. Although situational lubricants and regular moisturizers effectively pacify many symptoms, local estrogen is a safe, effective, and affordable way to treat the vulvovaginal changes of menopause.

Imagine: Multidrug-Resistant Acute Gonococcal Infection

What would happen if clinicians lost ceftriaxone as an effective therapy for gonococcal infection?

Probiotics Do Not Prevent C. difficile Infection in Hospitalized Patients

A retrospective cohort study from a single California hospital revealed the administration of probiotics to patients receiving antibiotics did not reduce the incidence of healthcare facility-onset Clostridioides difficile infection.

Does Physical Activity Lower the Risk of Parkinson’s Disease?

A systematic review and meta-analysis incorporating more than 500,000 subjects revealed that moderate to vigorous physical activity is associated with a significant reduction in development of Parkinson’s disease; this relationship is most pronounced in men.

Is There AV Block?

The long lead II rhythm strip in the figure was recorded at the standard 25 mm/second speed. This tracing was obtained from a middle-aged woman who presented to an outpatient clinic with noncardiac chest pain. How would one interpret this rhythm? Are there signs of AV block? Is it apparent if there is a cardiac problem?

Esketamine Nasal Spray (Spravato) CIII

Esketamine, in conjunction with an oral antidepressant, is indicated for the amelioration of treatment-resistant depression in adults.

Witness Observations in Diagnosing Transient Loss of Consciousness

Investigators found that adding witness-reported observations to patient demographics and patient-reported symptoms improved the diagnostic accuracy between epilepsy, syncope, and psychogenic nonepileptic seizures.