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In patients with suspected pulmonary tuberculosis who are unable to expectorate sputum, culture of 3 induced sputum samples, all collected on the same day, is an effective and efficient means of diagnosis.
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Gavalda and colleagues reported their experience with treating 43 patients with E. faecalis endocarditis using a combination of intravenous ampicillin 2 g every 4 hours and ceftriaxone 2 g every 12 hours for 6 weeks.
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In anticipation of the 2007-2008 influenza season, The CDC's Advisory Committee on Immunization Practices (ACIP) have updated their 2006 recommendations concerning the prevention and control of influenza.
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The FDA recently approved retapamulin (ALTABAX ) for topical treatment of impetigo due to Staphylococcus aureus and Streptococcus pyogenes in adults and in children 9 months of age or greater.
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In the past decade, prolongation of the QT interval associated with polymorphic ventricular tachycardia, or torsades de pointes (TdP), has accounted for the majority of withdrawals or restriction of the use of prescription drugs from the U.S. market.
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Lyme disease is the most commonly reported vector-borne disease in the U.S., with approximately 20,000 new cases reported each year. Most cases occur in northeastern, mid-Atlantic, and north central states (see Map), with peak incidences among those ages 5 to 14 years and 45 to 54 years.
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While use of aminoglycosides to treat gram negative rods has fallen over the last 30 years due to the availability of broad-spectrum beta lactam antibiotics, aminoglycoside antibiotics remain useful for the treatment of some life-threatening infections.
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Nearly one year following an in-depth report in the Wall Street Journal, and a brief synopsis in IDA (see June 2006, C. Kemper), this author, who was involved in the FDA review of telithromycin, provides a closer look at the events leading up to and following the FDA approval of telithromycin in the United States.
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Estrogen for Younger Postmenopausal Women; Warfarin Better for Atrial Fibrillation Patients; FDA Actions