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In patients with suspected pulmonary tuberculosis who are unable to expectorate sputum, culture of 3 induced sputum samples, all collected on the same day, is an effective and efficient means of diagnosis.
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A prodrug of dextroamphetamine has been approved by the FDA for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is the d-amphetamine covalently bound to l-lysine. It is marketed by Shire US Inc as Vyvanse.
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EMG studies are helpful in a minority of patients with suspected sacral plexopathy. Clinical examination and imaging provide more useful information.
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SSRIs are associated with a low rate of birth defects according to 2 new studies in the New England Journal of Medicine.
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The most common cause of bilateral vestibulopathy remains ototoxicity from antibiotics, such as gentamicin.
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The time to secondary progression and irreversible disability in childhood-onset MS is slower as compared to adult-onset disease. However, it occurs at a younger age.
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TCD and MRA have a low positive predictive value in diagnosing clinically significant intracranial stenosis, but are useful as screening tests to rule-out significant lesions.
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This is the first ever published phase I clinical trial testing gene therapy in Parkinson's disease( PD).
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A variety of peptide markers in the blood and CSF have been identified by proteomic techniques and should increase our ability to identify, at an early stage, those patients at risk for developing Alzheimer's dementia (AD).
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