Clinical Publication
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The Degree of Pyuria Can Help Determine Urinary Tract Infection in Elderly Women
Elderly women with a urinary tract infection recorded a higher median number of urinary leukocytes compared to uninfected controls, including those with asymptomatic bacteriuria. For 264 leukocytes/µL, the sensitivity and specificity of microscopy were 88%. Using the standard pyuria threshold of 10 leukocytes/µL gave a specificity of 36% and a sensitivity of 100%.
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Treating Psychotic Symptoms Among Alzheimer’s Disease Patients
In a meta-analysis of several large treatment trials of patients with Alzheimer’s disease, Parkinson’s disease, and dementia with Lewy bodies, cholinesterase inhibitors demonstrated a small but statistically significant benefit in alleviating psychotic symptoms.
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Comparing Sequelae After Hospitalization with COVID-19, Influenza, or Sepsis
The incidence of most selected new-onset medical conditions did not significantly differ among those who had been hospitalized with COVID-19, influenza, or sepsis.
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Reconsidering Aspirin Therapy for Elderly Patients
A post-hoc analysis of the ASPREE trial revealed that in presumably healthy elderly subjects, taking low-dose aspirin daily over three years was associated with a significant drop in hemoglobin and ferritin levels vs. placebo, even when patients with major bleeding events were excluded.
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Social Determinants Play Outsized Role in Black/White Cardiovascular Health Gap
Lower income levels, less education, tighter insurance access raise risk for cardiovascular disease mortality.
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The Importance of Diagnosing Obstructive Sleep Apnea During Pregnancy
Obstructive sleep apnea is associated with several adverse maternal and fetal outcomes.
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Comparing the Effects of Electroacupuncture and Auricular Acupuncture on Pain Control?
This randomized clinical trial involves 360 cancer survivors and found that two types of acupuncture demonstrated superior pain control compared to usual care during a 12-week follow-up period.
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Postpartum Depression Medication Headed to Market
FDA approves first oral solution.
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This Leadless Dual-Chamber Pacing System Is Coming
The initial 90-day experience with a dual-chamber leadless pacemaker system showed reliable atrial pacing and atrioventricular synchrony, with complication rates similar to conventional lead-based systems.
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Researchers Report on the Efficacy of the Subcutaneous Implantable Cardioverter-Defibrillator
An FDA-mandated post-approval study of the subcutaneous cardioverter-defibrillator system in a real-world population revealed excellent safety and efficacy over five years.