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Imetelstat Injection (Rytelo)

The U.S. Food and Drug Administration has approved a first-in-class telomerase inhibitor for the treatment of myelodysplastic syndrome with transfusion-dependent anemia.

Being Mindful of COVID’s Effects on Cognitive Decline

A large observational study finds objective evidence of lingering cognitive deficits associated with past COVID-19 infection, particularly in patients infected early in the pandemic, those hospitalized, or those with prolonged illness duration.

Summer Travel: News Clinicians (and Their Patients) Can Use

The pandemic has waned. Summer vacation has arrived. Airports are crowded. Planes are full. New science can guide us as we and our patients travel this season.

A Review of HIV Pre-Exposure Prophylaxis

Knowing one’s human immunodeficiency virus (HIV) status can help patients take steps to prevent transmission. Male and female condoms are options for preventing HIV during sexual intercourse. These products are widely available over the counter in retail stores and pharmacies and their use should be encouraged for preventing sexually transmitted infections. Yet, there is another option available, pre-exposure prophylaxis (PrEP), for patients to prevent HIV that many providers have not yet added to their armamentarium. This special feature will review the indications for PrEP, its use, and the medications recommended.

Comparing Medications Used for Lactation Inhibition

A randomized controlled trial demonstrated superior efficacy of cabergoline compared to pyridoxine (78% vs. 35%; P < 0.001) at suppression of lactation seven days after delivery.

How Common Is Cardiovascular Disease in Pregnant and Postpartum Women from Socioeconomically Disadvantaged Backgrounds?

Neighborhood-level socioeconomic inequities in early pregnancy were associated with higher risk of long-term cardiovascular disease in pregnant and postpartum women.

Maternal Mortality in the United States Is Worse than in any Other High-Income Nation

This article compares U.S. maternal mortality to other nations and explores reasons why mortality in the United States is four to 10 times higher than in peer countries.

Pivmecillinam Tablets (Pivya)

The U.S. Food and Drug Administration (FDA) has approved a new antibacterial for the treatment of uncomplicated urinary tract infection (UTI) in female adults.

Respiratory Syncytial Virus or Influenza in Older Patients: Which Is Worse?

In individuals 75 years of age or older, respiratory syncytial virus infection was associated with more severe illness than was influenza virus infection.

Avian Influenza A(H5N1) — From Birds to Cows to Human Infection

The spread of influenza H5N1 in dairy cows with documentation of a human infection raises pandemic concern.