Browse Clinical Publication Articles by Topic

Ambulatory Glucose Monitoring a Risk for Bloodborne Pathogens

A report of acute hepatitis B virus infection in a skilled nursing facility diabetes patient in North Carolina prompted an investigation for potential exposures and assessment of infection prevention practices in the facility.

Fleas, Typhus, and Texas

Cases of flea-borne typhus are dramatically increasing in Texas.

Detection of Atrial Fibrillation in Cryptogenic Stroke

The ANTARCTICA study is a pooled meta-analysis from multiple prospective studies of patients with ischemic stroke of varying etiologies, where loop monitoring was performed for atrial fibrillation detection. The groups were divided into cryptogenic stroke/transient ischemic attack or non-cryptogenic stroke/non-stroke. Both groups demonstrated an unadjusted rate of atrial fibrillation of about 30%.

Spironolactone for the Treatment of Acne Vulgaris

In this meta-analysis of 563 patients from five randomized controlled trials, objective assessment of acne improvement was higher in the spironolactone group compared to the placebo group (odds ratio, 6.59; 95% confidence interval, 3.50-12.43).

Early vs. Late Catheter Ablation for Atrial Fibrillation in Older Patients

An observational study from China in older patients with persistent atrial fibrillation (AF) has shown that an earlier diagnosis to catheter ablation time of ≤ 12 months compared to > 12 months is associated with lower rates of AF recurrence and adverse cardiovascular outcomes.

SWOT Analysis of Artificial Intelligence in Medicine

Artificial intelligence (AI) is rapidly transforming clinical workflows, especially by reducing documentation time and after-hours work, and improving work-life balance, with studies showing substantial drops in burnout within weeks of implementation. As AI systems continue to demonstrate strong medical knowledge and performance, they offer clinicians a powerful way to elevate accuracy, streamline tasks, and improve patient understanding without replacing clinical judgment.

Long-Term Outcomes of Peripartum Cardiomyopathy

A large, prospective, observational study from Israel of peripartum cardiomyopathy has shown that, in general, outcomes are favorable, with high rates of left ventricular function recovery that remain stable and with no mortality but also that show high rates of cardiovascular comorbidities during long-term follow-up.

Fertility-Sparing vs. Surgical Treatment for Stage I Endometrial Cancer

This retrospective cohort study using the National Cancer Database demonstrated similar overall survival between fertility-sparing treatment and hysterectomy for patients younger than 40 years of age with clinical stage 1, low-grade endometrial cancer (hazard ratio [HR], 1.00; 95% confidence interval [CI], 0.50-2.00) but an increased mortality risk for patients aged 40-49 years receiving fertility-sparing treatment (HR, 4.94; 95% CI, 1.89-12.91).

Spironolactone for the Treatment of Acne Vulgaris

In this meta-analysis of 563 patients from five randomized controlled trials, objective assessment of acne improvement was higher in the spironolactone group compared to the placebo group (odds ratio, 6.59; 95% confidence interval, 3.50-12.43).

Acetaminophen Use During Pregnancy and Neurodevelopmental Disorders

The synthesized evidence on prenatal acetaminophen exposure and neurodevelopmental outcomes highlights modest and inconsistent associations and emphasizes that causality remains unproven because of confounding and measurement biases. The authors conclude that, consistent with American College of Obstetricians and Gynecologists and Society for Maternal-Fetal Medicine guidance, acetaminophen remains appropriate in pregnancy when clinically indicated.